Expression of Geranylgeranyl Pyrophosphate Synthase (GGPS1)

Stable Identifier
R-HSA-1655832
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, cytosol
ReviewStatus
5/5
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Expression of Geranylgeranyl Pyrophosphate Synthase (GGPS1)
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The GGPS1 gene is transcribed to yield mRNA and the mRNA is translated to yield protein.

SREBF1A (SREBP1A) and SREBF2 (SREBP2) bind the promoter of the Geranylgeranyl pyrophosphate synthase gene (GGPS1) and enhance transcription (Sakakura et al. 2001, Reed et al. 2008, reviewed in Horton et al. 2002)

Literature References
PubMed ID Title Journal Year
18726356 cDNA cloning, chromosome mapping and expression characterization of human geranylgeranyl pyrophosphate synthase

Gao, J, Zhao, Y, Fu, Q, Hua, Y, Zhao, S, Zhang, H, Yu, L

Sci China C Life Sci 2000
Participants
Input
Output
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as an event of
This event is regulated
Positively by
Regulator
SREBP1A,2:NF-Y:SP1:GGPS1 gene [nucleoplasm] (Homo sapiens)
Authored
May, B  (2011-09-28)
Reviewed
Liang, G  (2012-08-26)
Created
May, B  (2011-10-13)
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