Expression of 7-Dehydrocholesterol Reductase (DHCR7)

Stable Identifier
R-HSA-1655827
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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The DHCR7 gene is transcribed to yield mRNA and the mRNA is translated to yield protein.

Literature References
PubMed ID Title Journal Year
9634533 Mutations in the human sterol delta7-reductase gene at 11q12-13 cause Smith-Lemli-Opitz syndrome

Wassif, CA, Maslen, C, Kachilele-Linjewile, S, Lin, D, Linck, LM, Connor, WE, Steiner, RD, Porter, FD

Am J Hum Genet 1998
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Summation

SREBF1A (SREBP1A) and SREBF2 (SREBP2) bind the promoter of the 7-Dehydrocholesterol Reductase (DHCR) gene and enhance transcription (Sakakura et al. 2001, Reed et al. 2008, reviewed in Horton et al. 2002).

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