Expression of Farnesyl Diphosphate Synthase (FDPS)

Stable Identifier
R-HSA-1655824
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, cytosol
ReviewStatus
5/5
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Expression of Farnesyl Diphosphate Synthase (FDPS)
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The FDPS gene is transcribed to yield mRNA and the mRNA is translated to yield protein. SREBF1A/1C/2 (SREBP1A/1C/2) and NF-Y bind the promoter of the Farnesyl Diphosphate Synthase (FDPS) gene and activate transcription (Ericsson et al. 1996, Jackson et al. 1996, Horton et al. 1998, Pai et al. 1998, Sakakura 2001, Amemiya-Kudo et al. 2002, Reed et al. 2008, Ishimoto et al. 2010, reviewed in Horton et al. 2002).
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This event is regulated
Positively by
Regulator
SREBP1A,1C,2:NF-Y:FDPS gene [nucleoplasm] (Homo sapiens)
Authored
May, B  (2011-09-28)
Reviewed
Liang, G  (2012-08-26)
Created
May, B  (2011-10-13)
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