Expression of Farnesyl Diphosphate Synthase (FDPS)

Stable Identifier
R-HSA-1655824
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
nucleoplasm, cytosol
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Expression of Farnesyl Diphosphate Synthase (FDPS)
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The FDPS gene is transcribed to yield mRNA and the mRNA is translated to yield protein.

SREBF1A/1C/2 (SREBP1A/1C/2) and NF-Y bind the promoter of the Farnesyl Diphosphate Synthase (FDPS) gene and activate transcription (Ericsson et al. 1996, Jackson et al. 1996, Horton et al. 1998, Pai et al. 1998, Sakakura 2001, Amemiya-Kudo et al. 2002, Reed et al. 2008, Ishimoto et al. 2010, reviewed in Horton et al. 2002).

Literature References
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
SREBP1A,1C,2:NF-Y:FDPS gene [nucleoplasm] (Homo sapiens)
Authored
May, B  (2011-09-28)
Reviewed
Liang, G  (2012-08-25)
Created
May, B  (2011-10-13)
Cite Us!