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SREBF1-1(1-490) [cytosol]
Stable Identifier
R-HSA-1655764
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
SREBF1A(1-490), SREBP1A(1-490), SREBF1A cleaved by S2P, Sterol regulatory element-binding protein 1A, SRBP1_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Regulation of cholesterol biosynthesis by SREBP (SREBF) (Homo sapiens)
S2P hydrolyzes SREBP1A,1C,2 (Homo sapiens)
SREBF1A,1C,2 cleaved by S2P [cytosol] (Homo sapiens)
SREBF1-1(1-490) [cytosol] (Homo sapiens)
SREBP1A,1C,2 binds Importin beta-1 (Homo sapiens)
SREBP1A,1C,2 dimer [cytosol] (Homo sapiens)
SREBF1A,1C,2 cleaved by S2P [cytosol] (Homo sapiens)
SREBF1-1(1-490) [cytosol] (Homo sapiens)
SREBP1A,1C,2:Importin beta-1 [cytosol] (Homo sapiens)
SREBP1A,1C,2 dimer [cytosol] (Homo sapiens)
SREBF1A,1C,2 cleaved by S2P [cytosol] (Homo sapiens)
SREBF1-1(1-490) [cytosol] (Homo sapiens)
SREBP1A,1C,2 binds SREBP1A,1C,2 forming dimers (Homo sapiens)
SREBF1A,1C,2 cleaved by S2P [cytosol] (Homo sapiens)
SREBF1-1(1-490) [cytosol] (Homo sapiens)
SREBP1A,1C,2 dimer [cytosol] (Homo sapiens)
SREBF1A,1C,2 cleaved by S2P [cytosol] (Homo sapiens)
SREBF1-1(1-490) [cytosol] (Homo sapiens)
SREBP1A,1C,2 translocates to the nucleus (Homo sapiens)
SREBP1A,1C,2:Importin beta-1 [cytosol] (Homo sapiens)
SREBP1A,1C,2 dimer [cytosol] (Homo sapiens)
SREBF1A,1C,2 cleaved by S2P [cytosol] (Homo sapiens)
SREBF1-1(1-490) [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P36956-1 SREBF1
Gene Names
SREBF1, BHLHD1, SREBP1
Participates
as a member of
SREBF1A,1C,2 cleaved by S2P [cytosol] (Homo sapiens)
Other forms of this molecule
SREBF1-1 [endoplasmic reticulum membrane]
SREBF1-1 [Golgi membrane]
SREBF1-1(1-530) [Golgi membrane]
SREBF1-1(1-490) [nucleoplasm]
Inferred To
SREBP [cytosol]
(Drosophila melanogaster)
Srebf1 [cytosol]
(Mus musculus)
Srebf1 [cytosol]
(Rattus norvegicus)
SREBF1 [cytosol]
(Bos taurus)
SREBF1 [cytosol]
(Canis familiaris)
SREBF1 [cytosol]
(Sus scrofa)
sbp-1 [cytosol]
(Caenorhabditis elegans)
SREBF1-1(1-490) [cytosol]
(Gallus gallus)
srebf1 [cytosol]
(Danio rerio)
srebf1 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_004167.3
,
NP_001005291.1
ENSEMBL
ENSP00000379106
,
ENST00000355815
,
ENSP00000261646
,
ENST00000395757
,
ENSP00000348069
,
ENST00000261646
,
ENSG00000072310
OpenTargets
ENSG00000072310
GeneCards
SREBF1
HPA
ENSG00000072310-SREBF1
PRO
P36956
Pharos - Targets
P36956
GlyGen
P36956
PDB
1AM9
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P54253 ATX1
0.666
5
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
3
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