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INSIG1 [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-1655735
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
Insulin-induced gene 1 protein, INSI1_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Regulation of cholesterol biosynthesis by SREBP (SREBF) (Homo sapiens)
SREBP1A,1C,2 binds SCAP:INSIG:oxysterol and is retained in the endoplasmic reticulum (Homo sapiens)
INSIG:oxysterol [endoplasmic reticulum membrane] (Homo sapiens)
INSIG [endoplasmic reticulum membrane] (Homo sapiens)
INSIG1 [endoplasmic reticulum membrane] (Homo sapiens)
SREBP1A,1C,2:SCAP:INSIG:oxysterol [endoplasmic reticulum membrane] (Homo sapiens)
INSIG:oxysterol [endoplasmic reticulum membrane] (Homo sapiens)
INSIG [endoplasmic reticulum membrane] (Homo sapiens)
INSIG1 [endoplasmic reticulum membrane] (Homo sapiens)
SREBP1A,1C,2 binds SCAP:cholesterol:INSIG and is retained in the endoplasmic reticulum (Homo sapiens)
INSIG [endoplasmic reticulum membrane] (Homo sapiens)
INSIG1 [endoplasmic reticulum membrane] (Homo sapiens)
SREBP1A,1C,2:SCAP:cholesterol:INSIG [endoplasmic reticulum membrane] (Homo sapiens)
INSIG [endoplasmic reticulum membrane] (Homo sapiens)
INSIG1 [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O15503 INSIG1
Gene Names
INSIG1
Chain
chain:1-277
Reference Genes
BioGPS Gene:3638 INSIG1
COSMIC (genes):INSIG1 INSIG1
CTD Gene:3638 INSIG1
dbSNP Gene:3638 INSIG1
ENSEMBL:ENSG00000186480 INSIG1
HGNC:6083 INSIG1
KEGG:hsa:3638 INSIG1
Monarch:3638 INSIG1
NCBI Gene:3638 INSIG1
OMIM:602055 INSIG1
UCSC:O15503 INSIG1
Reference Transcript
RefSeq:NM_001346594.1 INSIG1
RefSeq:NM_198336.3 INSIG1
RefSeq:NM_005542.5 INSIG1
RefSeq:NM_001346591.1 INSIG1
RefSeq:NM_001346593.2 INSIG1
RefSeq:NM_001346590.1 INSIG1
RefSeq:XM_017012177.1 INSIG1
RefSeq:NM_198337.4 INSIG1
RefSeq:NM_001346592.2 INSIG1
Other Identifiers
11716337_s_at
11716338_a_at
11716339_a_at
17053892
201625_PM_s_at
201625_s_at
201626_PM_at
201626_at
201627_PM_s_at
201627_s_at
3033230
3033231
3033232
3033233
3033234
3033235
3033236
3033237
3033238
3033239
3033240
3033241
3033242
3033244
3033245
3033247
3033248
3033249
3033250
3033251
3033255
3033256
3033257
3033258
3033259
35303_at
3638
8137526
87466_at
A_23_P22027
A_33_P3219090
GE59601
GE85346
GO:0005515
GO:0005783
GO:0005789
GO:0006607
GO:0006629
GO:0006641
GO:0006695
GO:0006886
GO:0006913
GO:0006991
GO:0008142
GO:0008202
GO:0008203
GO:0008289
GO:0010894
GO:0016020
GO:0016126
GO:0032869
GO:0032933
GO:0032937
GO:0036315
GO:0036316
GO:0042472
GO:0042474
GO:0042632
GO:0045541
GO:0045542
GO:0045599
GO:0045717
GO:0048856
GO:0051604
GO:0060021
GO:0060363
GO:0070862
GO:0140311
GO:1901303
HMNXSV003000213
Hs.56205.0.S1_3p_a_at
Hs.56205.0.S3_3p_at
ILMN_1686989
ILMN_1793474
PH_hs_0028376
TC07001039.hg
g5031800_3p_a_at
Participates
as a member of
INSIG [endoplasmic reticulum membrane] (Homo sapiens)
Cross References
RefSeq
NP_001333519.1
,
NP_001333523.1
,
NP_001333521.1
,
NP_001333522.1
,
NP_938150.2
,
XP_016867666.1
,
NP_938151.1
,
NP_005533.2
,
NP_001333520.1
ENSEMBL
ENST00000342407
,
ENSG00000186480
,
ENSP00000344741
,
ENSP00000344035
,
ENST00000340368
OpenTargets
ENSG00000186480
GeneCards
INSIG1
HPA
ENSG00000186480-INSIG1
PRO
O15503
Pharos - Targets
O15503
PDB
4J81
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