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SREBF1-3 [cytosol]
Stable Identifier
R-HSA-1655721
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
SREBF1C(1-466), SREBP1C(1-466), SREBF1C cleaved by S2P, Sterol regulatory element-binding protein 1C, SRBP1_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Regulation of cholesterol biosynthesis by SREBP (SREBF) (Homo sapiens)
S2P hydrolyzes SREBP1A,1C,2 (Homo sapiens)
SREBF1A,1C,2 cleaved by S2P [cytosol] (Homo sapiens)
SREBF1-3 [cytosol] (Homo sapiens)
SREBP1A,1C,2 binds Importin beta-1 (Homo sapiens)
SREBP1A,1C,2 dimer [cytosol] (Homo sapiens)
SREBF1A,1C,2 cleaved by S2P [cytosol] (Homo sapiens)
SREBF1-3 [cytosol] (Homo sapiens)
SREBP1A,1C,2:Importin beta-1 [cytosol] (Homo sapiens)
SREBP1A,1C,2 dimer [cytosol] (Homo sapiens)
SREBF1A,1C,2 cleaved by S2P [cytosol] (Homo sapiens)
SREBF1-3 [cytosol] (Homo sapiens)
SREBP1A,1C,2 binds SREBP1A,1C,2 forming dimers (Homo sapiens)
SREBF1A,1C,2 cleaved by S2P [cytosol] (Homo sapiens)
SREBF1-3 [cytosol] (Homo sapiens)
SREBP1A,1C,2 dimer [cytosol] (Homo sapiens)
SREBF1A,1C,2 cleaved by S2P [cytosol] (Homo sapiens)
SREBF1-3 [cytosol] (Homo sapiens)
SREBP1A,1C,2 translocates to the nucleus (Homo sapiens)
SREBP1A,1C,2:Importin beta-1 [cytosol] (Homo sapiens)
SREBP1A,1C,2 dimer [cytosol] (Homo sapiens)
SREBF1A,1C,2 cleaved by S2P [cytosol] (Homo sapiens)
SREBF1-3 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P36956-3 SREBF1
Gene Names
SREBF1, BHLHD1, SREBP1
Other Identifiers
11715959_a_at
11735120_a_at
11758738_a_at
1558875_PM_at
1558875_at
16841941
202308_PM_at
202308_at
32135_at
3747967
3747968
3747969
3747970
3747971
3747972
3747973
3747974
3747975
3747976
3747978
3747980
3747982
3747983
3747985
3747986
3747989
3747991
3747992
3747993
3747994
3747995
3747999
3748000
3748002
3748003
3748004
3748005
3748008
3748009
3748010
3748017
3748018
3748019
6720
73364_r_at
8013135
88057_at
A_23_P129786
A_24_P390784
A_33_P3222139
GE58843
GO:0000122
GO:0000139
GO:0000785
GO:0000977
GO:0000978
GO:0000981
GO:0001221
GO:0001228
GO:0003013
GO:0003062
GO:0003677
GO:0003682
GO:0003700
GO:0004879
GO:0005515
GO:0005634
GO:0005635
GO:0005654
GO:0005694
GO:0005737
GO:0005783
GO:0005789
GO:0005794
GO:0005829
GO:0006351
GO:0006355
GO:0006357
GO:0006366
GO:0006629
GO:0006695
GO:0006886
GO:0006914
GO:0007005
GO:0007584
GO:0007623
GO:0008202
GO:0008203
GO:0008286
GO:0008610
GO:0009267
GO:0009410
GO:0009749
GO:0009750
GO:0010867
GO:0010883
GO:0012507
GO:0014070
GO:0016020
GO:0016071
GO:0019217
GO:0019901
GO:0023052
GO:0030073
GO:0030154
GO:0030324
GO:0030522
GO:0031410
GO:0031647
GO:0032094
GO:0032526
GO:0032570
GO:0032810
GO:0032869
GO:0032933
GO:0032991
GO:0033762
GO:0033993
GO:0042789
GO:0043226
GO:0043434
GO:0043565
GO:0044877
GO:0045444
GO:0045471
GO:0045542
GO:0045893
GO:0045944
GO:0046676
GO:0046983
GO:0048856
GO:0050796
GO:0051591
GO:0060089
GO:0070542
GO:0071398
GO:0090209
GO:0140110
GO:1901524
GO:1902895
GO:1903214
GO:1990837
HMNXSV003020964
Hs2.424536.1.A1_3p_at
ILMN_1663035
ILMN_1695378
ILMN_2328986
PH_hs_0025189
PH_hs_0032079
TC17001192.hg
U00968_at
g4759167_3p_at
Participates
as a member of
SREBF1A,1C,2 cleaved by S2P [cytosol] (Homo sapiens)
Other forms of this molecule
SREBF1-3 [nucleoplasm]
SREBF1-3 [endoplasmic reticulum membrane]
SREBF1-3 [Golgi membrane]
SREBF1-3 [Golgi membrane]
Inferred To
SREBF1-3 [cytosol]
(Gallus gallus)
SREBP [cytosol]
(Drosophila melanogaster)
Srebf1 [cytosol]
(Mus musculus)
Srebf1 [cytosol]
(Rattus norvegicus)
SREBF1 [cytosol]
(Bos taurus)
SREBF1 [cytosol]
(Canis familiaris)
SREBF1 [cytosol]
(Sus scrofa)
sbp-1 [cytosol]
(Caenorhabditis elegans)
srebf1 [cytosol]
(Danio rerio)
srebf1 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_004167.3
,
NP_001005291.1
OpenTargets
ENSG00000072310
GeneCards
P36956
HPA
ENSG00000072310-SREBF1
Ensembl
ENSP00000261646
,
ENST00000261646
,
ENSP00000348069
,
ENST00000395757
,
ENSG00000072310
,
ENST00000355815
,
ENSP00000379106
PRO
P36956
Pharos - Targets
P36956
PDB
1AM9
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P54253 ATX1
0.666
5
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
3
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