PDE3B signalling

Stable Identifier
R-HSA-165160
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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PDE3B signalling
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AKT (PKB) is recruited to the plasma membrane by binding phosphatidylinositol (3,4,5)-trisphosphate (PIP3). AKT is then activated by phosphorylation. Activated AKT in turn phosphorylates Phosphodiesterase 3B (PDE3B) which hydrolyzes 3',5'-cyclic AMP (cAMP) (reviewed in Manning and Toker 2017).
Literature References
PubMed ID Title Journal Year
28431241 AKT/PKB Signaling: Navigating the Network

Manning, BD, Toker, A

Cell 2017
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Events
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Orthologous Events
PDE3B signalling (Bos taurus)
PDE3B signalling (Caenorhabditis elegans)
PDE3B signalling (Canis familiaris)
PDE3B signalling (Dictyostelium discoideum)
PDE3B signalling (Gallus gallus)
PDE3B signalling (Mus musculus)
PDE3B signalling (Plasmodium falciparum)
PDE3B signalling (Rattus norvegicus)
PDE3B signalling (Sus scrofa)
PDE3B signalling (Xenopus tropicalis)
Created
de Bono, B  (2005-08-01)
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