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Cytochrome c oxidase [mitochondrial inner membrane]
Stable Identifier
R-HSA-164316
Type
Complex
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
Complex IV
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
Cytoprotection by HMOX1 (Homo sapiens)
CO binds to Cytochrome c oxidase (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
Electron transfer from reduced cytochrome c to molecular oxygen (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Metabolic Genes (Homo sapiens)
Electron transfer from reduced cytochrome c to molecular oxygen (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Respiratory electron transport (Homo sapiens)
Complex IV assembly (Homo sapiens)
MT-CO3, COX6A,B,7A and NDUFA4 bind to holo-MT-CO1,2 complex (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
Electron transfer from reduced cytochrome c to molecular oxygen (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
30030519
Structure of the intact 14-subunit human cytochrome c oxidase
Guo, R
,
Zong, S
,
Yang, M
,
Gu, J
,
Liu, T
,
Wu, M
Cell Res
2018
Participants
components
COX catalytic core [mitochondrial inner membrane]
(Homo sapiens)
COX4I1,2 [mitochondrial inner membrane]
(Homo sapiens)
COX5A [mitochondrial inner membrane]
(Homo sapiens)
COX5B:Zn2+ [mitochondrial inner membrane]
(Homo sapiens)
COX6A:PE [mitochondrial inner membrane]
(Homo sapiens)
COX6B1,2 [mitochondrial inner membrane]
(Homo sapiens)
COX6C(3-75) [mitochondrial inner membrane]
(Homo sapiens)
COX7A1,2,2L [mitochondrial inner membrane]
(Homo sapiens)
COX7B [mitochondrial inner membrane]
(Homo sapiens)
COX7C [mitochondrial inner membrane]
(Homo sapiens)
COX8A,C [mitochondrial inner membrane]
(Homo sapiens)
NDUFA4:CL [mitochondrial inner membrane]
(Homo sapiens)
Participates
as an input of
CO binds to Cytochrome c oxidase (Homo sapiens)
as an output of
MT-CO3, COX6A,B,7A and NDUFA4 bind to holo-MT-CO1,2 complex (Homo sapiens)
as a component of
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Homo sapiens)
Inferred To
Cytochrome c oxidase [mitochondrial inner membrane]
(Bos taurus)
Cytochrome c oxidase [mitochondrial inner membrane]
(Canis familiaris)
Cytochrome c oxidase [mitochondrial inner membrane]
(Danio rerio)
Cytochrome c oxidase [mitochondrial inner membrane]
(Drosophila melanogaster)
Cytochrome c oxidase [mitochondrial inner membrane]
(Gallus gallus)
Cytochrome c oxidase [mitochondrial inner membrane]
(Mus musculus)
Cytochrome c oxidase [mitochondrial inner membrane]
(Rattus norvegicus)
Cytochrome c oxidase [mitochondrial inner membrane]
(Sus scrofa)
Cytochrome c oxidase [mitochondrial inner membrane]
(Xenopus tropicalis)
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