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MT-CO3 [mitochondrial inner membrane]
Stable Identifier
R-HSA-164312
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III
Icon
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
Cytoprotection by HMOX1 (Homo sapiens)
CO binds to Cytochrome c oxidase (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
MT-CO3 [mitochondrial inner membrane] (Homo sapiens)
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
MT-CO3 [mitochondrial inner membrane] (Homo sapiens)
Electron transfer from reduced cytochrome c to molecular oxygen (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
MT-CO3 [mitochondrial inner membrane] (Homo sapiens)
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
MT-CO3 [mitochondrial inner membrane] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Metabolic Genes (Homo sapiens)
Electron transfer from reduced cytochrome c to molecular oxygen (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
MT-CO3 [mitochondrial inner membrane] (Homo sapiens)
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
MT-CO3 [mitochondrial inner membrane] (Homo sapiens)
Metabolism (Homo sapiens)
The citric acid (TCA) cycle and respiratory electron transport (Homo sapiens)
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Homo sapiens)
Respiratory electron transport (Homo sapiens)
Electron transfer from reduced cytochrome c to molecular oxygen (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
MT-CO3 [mitochondrial inner membrane] (Homo sapiens)
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
MT-CO3 [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P00414 MT-CO3
Gene Names
MT-CO3, COIII, COXIII, MTCO3
Chain
chain:1-261
Reference Genes
BioGPS Gene:4514 MT-CO3
COSMIC (genes):MT-CO3 MT-CO3
CTD Gene:4514 MT-CO3
dbSNP Gene:4514 MT-CO3
ENSEMBL:ENSG00000198938 MT-CO3
ENSEMBL:ENSG00000198938.2 MT-CO3
HGNC:7422 MT-CO3
KEGG Gene (Homo sapiens):4514 MT-CO3
Monarch:4514 MT-CO3
NCBI Gene:4514 MT-CO3
OMIM:516050 MT-CO3
Reference Transcript
RefSeq:NC_012920.1 MT-CO3
Other Identifiers
11762922_s_at
11762923_x_at
1553588_PM_at
1553588_at
17100665
17100667
17100669
17100671
17126270
2315319
4037642
4037643
4037644
4037645
4037646
4037647
4037648
4037649
4037651
4037653
4037655
4037657
4037658
4037659
4514
8165669
8165672
8165674
A_23_P360209
A_33_P3336696
GO:0003824
GO:0004129
GO:0005215
GO:0005515
GO:0005739
GO:0005743
GO:0005751
GO:0006091
GO:0006123
GO:0008535
GO:0009055
GO:0016020
GO:0016491
GO:0019646
GO:0022904
GO:0043226
GO:0045277
GO:0045333
GO:0055085
GO:0065003
GO:1902600
HMNXSV003008622
HMNXSV003015713
Hs2Affx.1.41.S1_3p_s_at
Hs2Affx.1.52.S1_3p_at
PH_hs_0033947
PH_hs_0036541
TC0M000006.hg
TC0M000022.hg
Participates
as a component of
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
Inferred To
COX3 [mitochondrial inner membrane]
(Bos taurus)
COX3 [mitochondrial inner membrane]
(Canis familiaris)
MT-CO3 [mitochondrial inner membrane]
(Gallus gallus)
MT-CO3 [mitochondrial inner membrane]
(Sus scrofa)
mt:CoIII [mitochondrial inner membrane]
(Drosophila melanogaster)
Mtco3 [mitochondrial inner membrane]
(Rattus norvegicus)
mt-Co3 [mitochondrial inner membrane]
(Mus musculus)
mt-co3 [mitochondrial inner membrane]
(Danio rerio)
mt-co3 [mitochondrial inner membrane]
(Xenopus tropicalis)
Cross References
RefSeq
YP_003024032.1
OpenTargets
ENSG00000198938
IntEnz
7.1.1.9
HPA
ENSG00000198938-MT-CO3
GeneCards
P00414
Ensembl
ENST00000362079
,
ENSP00000354982
,
ENSG00000198938
PRO
P00414
Pharos - Targets
P00414
Orphanet
16473
HMDB Protein
HMDBP07034
PDB
5Z62
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P37840 SNCA
5
SNCA A30P [cytosol]
(R-HSA-5658569)
SNCA [extracellular region]
(R-HSA-976954)
Ub-SNCA [cytosol]
(R-HSA-5660754)
p-S129-SNCA [cytosol]
(R-HSA-9836432)
SNCA [cytosol]
(R-HSA-5658500)
0.508
3
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