Reactome | COX7A2L [mitochondrial inner membrane]

COX7A2L [mitochondrial inner membrane]

Stable Identifier

R-HSA-164310

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Cytochrome c oxidase subunit VIIa-related protein, COX7a-related protein

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional Regulation by TP53 (Homo sapiens)
      - TP53 Regulates Metabolic Genes (Homo sapiens)
        
        Electron transfer from reduced cytochrome c to molecular oxygen (Homo sapiens)
        
        Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
        
        COX7A1,2,2L [mitochondrial inner membrane] (Homo sapiens)
        
        COX7A2L [mitochondrial inner membrane] (Homo sapiens)
        
        Cytochrome c oxidase:CO [mitochondrial inner membrane] (Homo sapiens)
        
        Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
        
        COX7A1,2,2L [mitochondrial inner membrane] (Homo sapiens)
        
        COX7A2L [mitochondrial inner membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:O14548 COX7A2L

Gene Names

COX7A2L, COX7AR, COX7RP

Chain

transit peptide:1-55, chain:56-114

Reference Genes

BioGPS Gene:9167 COX7A2L

COSMIC (genes):COX7A2L COX7A2L

CTD Gene:9167 COX7A2L

dbSNP Gene:9167 COX7A2L

ENSEMBL:ENSG00000115944 COX7A2L

HGNC:2289 COX7A2L

KEGG:hsa:9167 COX7A2L

Monarch:9167 COX7A2L

NCBI Gene:9167 COX7A2L

OMIM:605771 COX7A2L

UCSC:O14548 COX7A2L

Reference Transcript

Other Identifiers

11715990_s_at

11754023_a_at

16896882

16896897

201256_PM_at

201256_at

2550138

2550139

2550140

2550141

2550142

2550143

2550144

2550148

2550149

2550150

2550151

2550152

2550154

2550155

2550157

2550158

2550160

2550161

2550172

34330_at

8051777

83313_at

9167

A_21_P0002428

A_23_P210348

A_24_P88800

GE551758

GO:0002082

GO:0003824

GO:0004129

GO:0005215

GO:0005730

GO:0005739

GO:0005743

GO:0005746

GO:0005751

GO:0006091

GO:0006123

GO:0007005

GO:0016491

GO:0043226

GO:0055085

GO:0065003

GO:0097250

GO:0098803

GO:1902600

HMNXSV003008691

HMNXSV003046138

PH_hs_0025165

PH_hs_0033277

TC02001778.hg

TC02001779.hg

TC02004187.hg

g4758041_3p_at

p20815

p9098

Participates

as a member of

COX7A1,2,2L [mitochondrial inner membrane] (Homo sapiens)

Inferred To

Homologues of COX7A2L [mitochondrial inner membrane] (Drosophila melanogaster)

COX7AL [mitochondrial inner membrane] (Drosophila melanogaster)

COX7A2L [mitochondrial inner membrane] (Bos taurus)

COX7A2L [mitochondrial inner membrane] (Canis familiaris)

COX7A2L [mitochondrial inner membrane] (Gallus gallus)

COX7A2L [mitochondrial inner membrane] (Sus scrofa)

COX7A [mitochondrial inner membrane] (Drosophila melanogaster)

Cox7a2l [mitochondrial inner membrane] (Mus musculus)

Cox7a2l [mitochondrial inner membrane] (Rattus norvegicus)

cox7a2l [mitochondrial inner membrane] (Danio rerio)

cox7a2l [mitochondrial inner membrane] (Xenopus tropicalis)

COX7AL2 [mitochondrial inner membrane] (Drosophila melanogaster)

Cross References

ENSEMBL

ENSP00000367938, ENST00000234301, ENST00000378669, ENSP00000234301

OpenTargets

ENSG00000115944

HPA

ENSG00000115944-COX7A2L

PRO

O14548

Pharos - Targets

O14548

HMDB Protein

HMDBP03296

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O14949 UQCRQ	1	UQCRQ [mitochondrial inner membrane] (R-HSA-164283)	0.527	2
UniProt:P14927 UQCRB	1	UQCRB [mitochondrial inner membrane] (R-HSA-164287)	0.527	3
UniProt:P07919 UQCRH	1	UQCRH [mitochondrial inner membrane] (R-HSA-164286)	0.527	2