Ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENPP7) hydrolyses sphingomyelin

Stable Identifier
R-HSA-1640164
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Membrane-bound ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENPP7) mediates the hydrolysis of sphingomyelin to ceramide and choline phosphate (Duan et al. 2003, Wu et al. 2005).

Literature References
PubMed ID Title Journal Year
12885774 Identification of human intestinal alkaline sphingomyelinase as a novel ecto-enzyme related to the nucleotide phosphodiesterase family

Nelander, S, Cheng, Y, Bergman, T, Duan, RD, Xu, N, Palmberg, C, Duan, J, Wu, J, Nilsson, A

J Biol Chem 2003
15458386 Functional studies of human intestinal alkaline sphingomyelinase by deglycosylation and mutagenesis

Hansen, GH, Duan, RD, Wu, J, Nilsson, A

Biochem J 2005
Participants
Participates
Catalyst Activity

sphingomyelin phosphodiesterase activity of ENPP7 [plasma membrane]

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