Ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENPP7) hydrolyses sphingomyelin

Stable Identifier
R-HSA-1640164
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Membrane-bound ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENPP7) mediates the hydrolysis of sphingomyelin to ceramide and choline phosphate (Duan et al. 2003, Wu et al. 2005).

Literature References
PubMed ID Title Journal Year
15458386 Functional studies of human intestinal alkaline sphingomyelinase by deglycosylation and mutagenesis

Wu, J, Hansen, GH, Nilsson, A, Duan, RD

Biochem J 2005
12885774 Identification of human intestinal alkaline sphingomyelinase as a novel ecto-enzyme related to the nucleotide phosphodiesterase family

Duan, RD, Bergman, T, Xu, N, Wu, J, Cheng, Y, Duan, J, Nelander, S, Palmberg, C, Nilsson, A

J Biol Chem 2003
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
sphingomyelin phosphodiesterase activity of ENPP7 [plasma membrane]
Physical Entity
Activity
Orthologous Events
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