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NDUFS6 [mitochondrial inner membrane]
Stable Identifier
R-HSA-163922
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
NADH-ubiquinone oxidoreductase 13 kDa-A subunit
Locations in the PathwayBrowser for interactor UniProt:O00217 NDUFS8
Expand all
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Respiratory electron transport (Homo sapiens)
Complex I biogenesis (Homo sapiens)
NDUF subunits bind to form the FP subcomplex (Homo sapiens)
NDUFS6 [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O75380 NDUFS6
Gene Names
NDUFS6
Chain
transit peptide:1-28, chain:29-124
Reference Genes
BioGPS Gene:4726 NDUFS6
COSMIC (genes):NDUFS6 NDUFS6
CTD Gene:4726 NDUFS6
dbSNP Gene:4726 NDUFS6
ENSEMBL:ENSG00000145494 NDUFS6
ENSEMBL_homo_sapiens_GENE:ENSG00000145494.12 NDUFS6
HGNC:7713 NDUFS6
KEGG Gene (Homo sapiens):4726 NDUFS6
Monarch:4726 NDUFS6
NCBI Gene:4726 NDUFS6
OMIM:603848 NDUFS6
Reference Transcript
RefSeq:NM_004553.4 NDUFS6
Other Identifiers
11716116_at
16982735
203606_PM_at
203606_at
2799204
2799207
2799215
2799216
2799217
34865_at
4726
8104298
A_23_P122228
GE79981
GO:0003824
GO:0005215
GO:0005739
GO:0005743
GO:0005747
GO:0006091
GO:0006120
GO:0008137
GO:0009055
GO:0009060
GO:0016020
GO:0016491
GO:0042776
GO:0043226
GO:0055086
GO:0070469
GO:1901135
PH_hs_0024741
TC05000019.hg
g4758791_3p_at
Participates
as a component of
FP subcomplex [mitochondrial inner membrane] (Homo sapiens)
FP subcomplex (-NDUFAF2) [mitochondrial inner membrane] (Homo sapiens)
as an input of
NDUF subunits bind to form the FP subcomplex (Homo sapiens)
Inferred To
NDUFS6 [mitochondrial inner membrane]
(Bos taurus)
NDUFS6 [mitochondrial inner membrane]
(Canis familiaris)
NDUFS6 [mitochondrial inner membrane]
(Gallus gallus)
NDUFS6 [mitochondrial inner membrane]
(Sus scrofa)
Ndufs6 [mitochondrial inner membrane]
(Mus musculus)
Ndufs6 [mitochondrial inner membrane]
(Rattus norvegicus)
ND-13A [mitochondrial inner membrane]
(Drosophila melanogaster)
nduf-6 [mitochondrial inner membrane]
(Caenorhabditis elegans)
ndufs6 [mitochondrial inner membrane]
(Danio rerio)
ndufs6 [mitochondrial inner membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_004544.1
OpenTargets
ENSG00000145494
HPA
ENSG00000145494-NDUFS6
GeneCards
O75380
Ensembl
ENST00000274137
,
ENSP00000274137
,
ENSG00000145494
PRO
O75380
Pharos - Targets
O75380
Orphanet
16530
HMDB Protein
HMDBP00191
PDB
5XTD
,
5XTI
,
5XTH
,
5XTB
Interactors (51)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O75489 NDUFS3
2
NDUFS3 [mitochondrial matrix]
(R-HSA-163927)
NDUFS3 [cytosol]
(R-HSA-9714751)
0.725
9
UniProt:O43678 NDUFA2
1
NDUFA2 [mitochondrial inner membrane]
(R-HSA-60178)
0.669
6
UniProt:O95182 NDUFA7
1
NDUFA7 [mitochondrial inner membrane]
(R-HSA-59858)
0.643
5
UniProt:O00217 NDUFS8
1
NDUFS8 [mitochondrial matrix]
(R-HSA-6788526)
0.643
5
UniProt:O75306 NDUFS2
1
NDUFS2 [mitochondrial matrix]
(R-HSA-6788520)
0.643
5
UniProt:P28331 NDUFS1
1
NDUFS1 [mitochondrial matrix]
(R-HSA-6788513)
0.643
5
UniProt:P56556 NDUFA6
1
NDUFA6 [mitochondrial inner membrane]
(R-HSA-59932)
0.643
5
UniProt:Q16795 NDUFA9
1
NDUFA9 [mitochondrial matrix]
(R-HSA-163942)
0.643
6
UniProt:Q9UI09 NDUFA12
1
NDUFA12 [mitochondrial inner membrane]
(R-HSA-59864)
0.643
5
UniProt:O43920 NDUFS5
1
NDUFS5 [mitochondrial inner membrane]
(R-HSA-60226)
0.643
5
UniProt:P03905 MT-ND4
1
MT-ND4 [mitochondrial inner membrane]
(R-HSA-60561)
0.643
5
UniProt:P19404 NDUFV2
1
NDUFV2 [mitochondrial inner membrane]
(R-HSA-163939)
0.643
5
UniProt:Q9H871 RMND5A
1
RMND5A [cytosol]
(R-HSA-9861580)
0.527
4
UniProt:O75251 NDUFS7
1
NDUFS7 [mitochondrial matrix]
(R-HSA-6788521)
0.527
5
UniProt:Q96LL9 DJC30
0.527
4
UniProt:Q9Y6M9 NDUFB9
1
NDUFB9 [mitochondrial inner membrane]
(R-HSA-60176)
0.527
4
UniProt:Q08830 FGL1
0.527
2
UniProt:Q9H0C8 ILKAP
0.527
3
UniProt:O95292 VAPB
2
VAPB [endoplasmic reticulum membrane]
(R-HSA-429718)
VAPB [Golgi membrane]
(R-HSA-9715115)
0.527
2
UniProt:P17568 NDUFB7
1
NDUFB7 [mitochondrial inner membrane]
(R-HSA-59940)
0.527
4
UniProt:O95298 NDUFC2
3
NDUFC2 [plasma membrane]
(R-HSA-6806276)
NDUFC2 [azurophil granule membrane]
(R-HSA-6799211)
NDUFC2 [mitochondrial inner membrane]
(R-HSA-59860)
0.527
4
UniProt:O15382 BCAT2
1
PXLP-BCAT2 [mitochondrial matrix]
(R-HSA-70703)
0.527
4
UniProt:Q8NCL4 GALNT6
1
GALNT6 [Golgi membrane]
(R-HSA-913608)
0.527
2
UniProt:Q96E35 ZMY19
0.527
3
UniProt:P51970 NDUFA8
1
NDUFA8 [mitochondrial inner membrane]
(R-HSA-60627)
0.527
3
UniProt:P03891 MT-ND2
1
MT-ND2 [mitochondrial inner membrane]
(R-HSA-60553)
0.527
3
UniProt:O95167 NDUFA3
1
NDUFA3 [mitochondrial inner membrane]
(R-HSA-60180)
0.527
4
UniProt:O95168 NDUFB4
1
NDUFB4 [mitochondrial inner membrane]
(R-HSA-59934)
0.527
4
UniProt:O75438 NDUFB1
1
NDUFB1 [mitochondrial inner membrane]
(R-HSA-60214)
0.527
4
UniProt:Q9NWU2 GID8
1
GID8 [cytosol]
(R-HSA-9861665)
0.527
4
UniProt:O95169 NDUFB8
4
NDUFB8 [mitochondrial inner membrane]
(R-HSA-163938)
NDUFB8(1-28) [mitochondrial matrix]
(R-HSA-8986166)
NDUFB8(1-186) [mitochondrial inner membrane]
(R-HSA-8986184)
NDUFB8(1-186) [mitochondrial intermembrane space]
(R-HSA-8986140)
0.527
4
UniProt:O43676 NDUFB3
1
NDUFB3 [mitochondrial inner membrane]
(R-HSA-59930)
0.527
4
UniProt:O43674 NDUFB5
1
NDUFB5 [mitochondrial inner membrane]
(R-HSA-163944)
0.527
4
UniProt:Q86YB7 ECHD2
0.527
2
UniProt:Q8IVV7 GID4
1
GID4 [cytosol]
(R-HSA-9861538)
0.527
4
UniProt:O96000 NDUFB10
1
NDUFB10 [mitochondrial inner membrane]
(R-HSA-60194)
0.527
4
UniProt:O75600 GCAT
1
PXLP-K265-GCAT [mitochondrial inner membrane]
(R-HSA-535614)
0.527
3
UniProt:O15239 NDUFA1
1
NDUFA1 [mitochondrial inner membrane]
(R-HSA-60212)
0.527
3
UniProt:Q16822 PCK2
1
PCK2 [mitochondrial matrix]
(R-HSA-372815)
0.527
2
UniProt:P49821 NDUFV1
1
NDUFV1 [mitochondrial inner membrane]
(R-HSA-163926)
0.527
4
UniProt:P03886 MT-ND1
1
MT-ND1 [mitochondrial inner membrane]
(R-HSA-60551)
0.527
4
UniProt:P03915 MT-ND5
1
MT-ND5 [mitochondrial inner membrane]
(R-HSA-60565)
0.527
4
UniProt:O43181 NDUFS4
1
NDUFS4 [mitochondrial inner membrane]
(R-HSA-163946)
0.527
4
UniProt:O95139 NDUFB6
1
NDUFB6 [mitochondrial inner membrane]
(R-HSA-59938)
0.527
4
UniProt:P13196 ALAS1
2
PXLP-ALAS1 [mitochondrial matrix]
(R-HSA-1022086)
ALAS1 [mitochondrial matrix]
(R-HSA-189438)
0.527
4
UniProt:Q9HC36 MRM3
1
RNMTL1 [mitochondrial matrix]
(R-HSA-6793067)
0.527
2
UniProt:P25103 TACR1
2
TACR1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869122)
TACR1 [plasma membrane]
(R-HSA-380103)
0.527
2
UniProt:Q6VN20 RANBP10
1
RANBP10 [cytosol]
(R-HSA-8851865)
0.527
4
UniProt:Q9P0J0 NDUFA13
8
NDUFA13 [mitochondrial inner membrane]
(R-HSA-59936)
NDUFA13(41-49) [mitochondrial inner membrane]
(R-HSA-9839958)
NDUFA13(100-108) [mitochondrial inner membrane]
(R-HSA-9839959)
NDUFA13(109-144) [mitochondrial inner membrane]
(R-HSA-9839968)
NDUFA13(2-19) [mitochondrial inner membrane]
(R-HSA-9839966)
NDUFA13(69-99) [mitochondrial inner membrane]
(R-HSA-9839964)
NDUFA13(20-40) [mitochondrial inner membrane]
(R-HSA-9839963)
NDUFA13(50-68) [mitochondrial inner membrane]
(R-HSA-9839961)
0.527
3
UniProt:P56181 NDUFV3
1
NDUFV3 [mitochondrial inner membrane]
(R-HSA-163943)
0.527
4
UniProt:O14561 NDUFAB1
4
Mal-PPANT-S112-NDUFAB1 [mitochondrial inner membrane]
(R-HSA-8934586)
PPANT-S112-NDUFAB1 [mitochondrial inner membrane]
(R-HSA-8933545)
octanoyl-S112-NDUFAB1 [mitochondrial inner membrane]
(R-HSA-9857608)
NDUFAB1 [mitochondrial inner membrane]
(R-HSA-163925)
0.527
2
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