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11xCbxE-GAS6(39-691) [Golgi lumen]
Stable Identifier
R-HSA-163844
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
GAS6, growth-arrest-specific protein 6
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Homo sapiens)
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins (Homo sapiens)
Removal of aminoterminal propeptides from gamma-carboxylated proteins (Homo sapiens)
Furin cleaves pro-GAS6 to GAS6 (Homo sapiens)
11xCbxE-GAS6(39-691) [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q14393 GAS6
Gene Names
GAS6, AXLLG
Chain
signal peptide:1-30, chain:31-678
Reference Genes
BioGPS Gene:2621 GAS6
COSMIC (genes):GAS6 GAS6
CTD Gene:2621 GAS6
dbSNP Gene:2621 GAS6
ENSEMBL:ENSG00000183087 GAS6
HGNC:4168 GAS6
KEGG:hsa:2621 GAS6
Monarch:2621 GAS6
NCBI Gene:2621 GAS6
OMIM:600441 GAS6
UCSC:Q14393 GAS6
Reference Transcript
RefSeq:NM_000820.3 GAS6
Other Identifiers
11715551_s_at
11754440_s_at
1597_at
1598_PM_g_at
1598_g_at
16781285
202177_PM_at
202177_at
2621
3502837
3502838
3502839
3502856
3502857
3502858
3502859
3502860
3502866
3502868
3502870
3502871
3502877
3502883
3502884
3502885
3502886
3502887
3502888
3502889
3502893
3502897
3502903
3502904
3502905
3502906
3502907
3502908
3502909
3502910
3502911
3502912
3502913
3502914
3502915
3502916
3502917
37658_at
7970329
A_14_P125887
A_23_P146922
A_33_P3352085
GE57632
GO:0001764
GO:0001786
GO:0001934
GO:0001961
GO:0002376
GO:0003014
GO:0003104
GO:0005102
GO:0005509
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005783
GO:0005788
GO:0005796
GO:0006355
GO:0006468
GO:0006909
GO:0006915
GO:0007155
GO:0007165
GO:0007166
GO:0007167
GO:0007596
GO:0008289
GO:0009267
GO:0010628
GO:0010804
GO:0012501
GO:0016192
GO:0019064
GO:0019079
GO:0030154
GO:0030198
GO:0030674
GO:0030971
GO:0031093
GO:0031100
GO:0031589
GO:0032008
GO:0032148
GO:0032689
GO:0032692
GO:0032715
GO:0032720
GO:0032825
GO:0033028
GO:0033033
GO:0035457
GO:0035754
GO:0043027
GO:0043066
GO:0043154
GO:0043226
GO:0043277
GO:0044346
GO:0045860
GO:0045892
GO:0046718
GO:0046813
GO:0046827
GO:0046872
GO:0048018
GO:0048146
GO:0048856
GO:0048870
GO:0050766
GO:0051897
GO:0055085
GO:0060090
GO:0061024
GO:0070062
GO:0070168
GO:0070374
GO:0070588
GO:0071307
GO:0071333
GO:0071363
GO:0071466
GO:0072659
GO:0085029
GO:0097028
GO:0097241
GO:0098772
GO:1900142
GO:2000270
GO:2000352
GO:2000510
GO:2000533
GO:2000669
HMNXSV003017087
HMNXSV003048686
ILMN_1768260
ILMN_1779558
ILMN_1781614
ILMN_1784749
L13720_3p_s_at
L13720_at
PH_hs_0025635
TC13000899.hg
g4557616_3p_s_at
Participates
as an output of
Furin cleaves pro-GAS6 to GAS6 (Homo sapiens)
Other forms of this molecule
GAS6 [endoplasmic reticulum lumen]
p-GAS6 [endoplasmic reticulum lumen]
11xCbxE-GAS6(39-691) [extracellular region]
GAS6(31-691) [endoplasmic reticulum lumen]
11xCbxE-GAS6(31-691) [endoplasmic reticulum lumen]
11xCbxE-GAS6(31-691) [Golgi lumen]
GAS6(31-38) [Golgi lumen]
GAS6(39-691) [platelet alpha granule lumen]
GAS6(39-691) [extracellular region]
Inferred To
11xCbxE-GAS6(39-691) [Golgi lumen]
(Gallus gallus)
11xCbxE-GAS6(39-691) [Golgi lumen]
(Mus musculus)
11xCbxE-GAS6(39-691) [Golgi lumen]
(Rattus norvegicus)
GAS6 [Golgi lumen]
(Bos taurus)
GAS6 [Golgi lumen]
(Canis familiaris)
GAS6 [Golgi lumen]
(Sus scrofa)
gas6 [Golgi lumen]
(Danio rerio)
gas6 [Golgi lumen]
(Xenopus tropicalis)
Modified Residues
Name
L-gamma-carboxyglutamic acid at 54
Coordinate
54
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 55
Coordinate
55
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 62
Coordinate
62
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 64
Coordinate
64
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 67
Coordinate
67
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 68
Coordinate
68
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 73
Coordinate
73
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 74
Coordinate
74
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 77
Coordinate
77
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 80
Coordinate
80
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 84
Coordinate
84
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Cross References
RefSeq
NP_000811.1
OpenTargets
ENSG00000183087
ENSEMBL
ENSP00000331831
,
ENST00000327773
HPA
ENSG00000183087-GAS6
PRO
Q14393
Pharos - Targets
Q14393
GlyGen
Q14393
PDB
5VXZ
,
4RA0
,
2C5D
,
1H30
HMDB Protein
HMDBP02012
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