CUX1-FGFR1 fusion mutant dimer

Stable Identifier
R-HSA-1637880
Type
Complex
Species
Homo sapiens
Compartment
Synonyms
CUX1(1-339)-FGFR1(429-822) fusion dimer, t(7;8) CUX1-FGFR1 fusion dimer
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
21330321 The kinase inhibitor TKI258 is active against the novel CUX1-FGFR1 fusion detected in a patient with T-lymphoblastic leukemia/lymphoma and t(7;8)(q22;p11)

Wasag, B, Lierman, E, Meeus, P, Cools, J, Vandenberghe, P

Haematologica 2011
Participants
Participant Of
Disease
Name Identifier Synonyms
precursor lymphoblastic lymphoma/leukemia 5600
subacute leukemia 3264
myelodysplastic myeloproliferative cancer 4972 Myeloproliferative/Myelodysplastic syndromes, unclassifiable myelodysplastic myeloproliferative disease, Unclassifiable Myeloproliferative/Myelodysplastic syndrome, Myelodysplastic/myeloproliferative disease (morphologic abnormality)