CUX1-FGFR1 fusion mutant dimer [cytosol]

Stable Identifier
R-HSA-1637880
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Synonyms
CUX1(1-339)-FGFR1(429-822) fusion dimer, t(7;8) CUX1-FGFR1 fusion dimer
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Literature References
PubMed ID Title Journal Year
21330321 The kinase inhibitor TKI258 is active against the novel CUX1-FGFR1 fusion detected in a patient with T-lymphoblastic leukemia/lymphoma and t(7;8)(q22;p11)

Wasag, B, Vandenberghe, P, Meeus, P, Lierman, E, Cools, J

Haematologica 2011
Participants
components
Participates
as a member of
Disease
Name Identifier Synonyms
subacute leukemia DOID:3264
precursor lymphoblastic lymphoma/leukemia DOID:5600
myelodysplastic myeloproliferative cancer DOID:4972 Myeloproliferative/Myelodysplastic syndromes, unclassifiable myelodysplastic myeloproliferative disease, Unclassifiable Myeloproliferative/Myelodysplastic syndrome, Myelodysplastic/myeloproliferative disease (morphologic abnormality)
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