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MGLL [lipid droplet]
Stable Identifier
R-HSA-163567
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lipid droplet
Synonyms
Monoglyceride lipase, MAGL, MGL
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
Epigenetic regulation by WDR5-containing histone modifying complexes (Homo sapiens)
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes (Homo sapiens)
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes (Homo sapiens)
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis (Homo sapiens)
MGLL gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex (Homo sapiens)
MGLL [lipid droplet] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Triglyceride metabolism (Homo sapiens)
Triglyceride catabolism (Homo sapiens)
2-acylglycerol + H2O -> glycerol + fatty acid (Homo sapiens)
MGLL [lipid droplet] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q99685 MGLL
Gene Names
MGLL
Chain
chain:1-303
Reference Genes
BioGPS Gene:11343 MGLL
COSMIC (genes):MGLL MGLL
CTD Gene:11343 MGLL
dbSNP Gene:11343 MGLL
ENSEMBL:ENSG00000074416 MGLL
HGNC:17038 MGLL
KEGG:hsa:11343 MGLL
Monarch:11343 MGLL
NCBI Gene:11343 MGLL
OMIM:609699 MGLL
UCSC:Q99685 MGLL
Reference Transcript
RefSeq:NM_001003794.2 MGLL
RefSeq:NM_007283.6 MGLL
RefSeq:NM_001256585.1 MGLL
Other Identifiers
11343
11717763_a_at
11717764_x_at
11717765_a_at
11717766_a_at
11750244_a_at
11750245_x_at
211026_PM_s_at
211026_s_at
225102_PM_at
225102_at
2694002
2694003
2694004
2694005
2694006
2694007
2694010
2694011
2694018
2694019
2694020
2694021
2694022
2694023
2694024
2694025
2694028
2694029
2694030
2694031
2694043
2694044
2694045
2694056
2694057
2694058
2694059
2694061
2694062
2694069
2694070
2694071
2694072
2694076
2694083
2694110
2694113
35792_at
51988_at
70703_at
8090433
A_24_P226008
A_33_P3281795
GE54874
GE59353
GE85097
GO:0003824
GO:0004622
GO:0005515
GO:0005737
GO:0005789
GO:0005829
GO:0005886
GO:0006629
GO:0006633
GO:0006639
GO:0006954
GO:0009966
GO:0016020
GO:0016042
GO:0016787
GO:0019369
GO:0019433
GO:0042803
GO:0046464
GO:0047372
GO:0050727
GO:0051930
GO:0052651
GO:0052689
GO:2000124
HMNXSV003003176
Hs.3964.0.S1_3p_at
ILMN_1657708
ILMN_1684280
ILMN_1707310
ILMN_1738589
PH_hs_0033207
U67963_at
g13623260_3p_s_at
Participates
as an output of
MGLL gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex (Homo sapiens)
Other forms of this molecule
MGLL [plasma membrane]
MGLL [endoplasmic reticulum membrane]
Cross References
ZINC - World Drugs
MGLL_HUMAN
Guide to Pharmacology - Targets
1399
OpenTargets
ENSG00000074416
ENSEMBL
ENST00000453507
,
ENST00000398104
,
ENSP00000404146
,
ENSP00000381176
ZINC - FDA approved
MGLL_HUMAN
ZINC - Substances
MGLL_HUMAN
ZINC target
Q99685
PRO
Q99685
GlyGen
Q99685
PDB
8PTC
,
6BQ0
,
7L4W
,
3JWE
,
6AX1
,
7ZPG
,
3PE6
,
3JW8
,
7L50
,
3HJU
,
8PTQ
,
8AQF
,
5ZUN
,
7L4U
,
7PRM
,
8PTR
,
4UUQ
,
7L4T
HPA
ENSG00000074416-MGLL
Pharos - Targets
Q99685
ZINC - Predictions - Purchasable
MGLL_HUMAN
HMDB Protein
HMDBP00314
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P37235 HPCL1
0.641
3
UniProt:Q5T0L3 SPT46
0.527
2
UniProt:P07550 ADRB2
5
ADRB2 [plasma membrane]
(R-HSA-390647)
pS-ADRB2 [plasma membrane]
(R-HSA-8852158)
PolyUb-ADRB2 [endosome membrane]
(R-HSA-6783066)
ADRB2 [endosome membrane]
(R-HSA-6783036)
pS-ADRB2 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869143)
0.508
2
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