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p-S81,S277-PLIN1 [lipid droplet]
Stable Identifier
R-HSA-163561
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lipid droplet
Synonyms
p-S277,S81-PLIN1, phosphorylated perilipin
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Triglyceride metabolism (Homo sapiens)
Triglyceride catabolism (Homo sapiens)
perilipin + 2 ATP -> phosphorylated perilipin + 2 ADP (Homo sapiens)
p-S81,S277-PLIN1 [lipid droplet] (Homo sapiens)
phosphorylated perilipin + H2O -> perilipin + orthophosphate (Homo sapiens)
p-S81,S277-PLIN1 [lipid droplet] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60240 PLIN1
Gene Names
PLIN1, PERI, PLIN
Chain
chain:1-522
Reference Genes
BioGPS Gene:5346 PLIN1
COSMIC (genes):PLIN1 PLIN1
CTD Gene:5346 PLIN1
dbSNP Gene:5346 PLIN1
ENSEMBL:ENSG00000166819 PLIN1
ENSEMBL_homo_sapiens_GENE:ENSG00000166819.12 PLIN1
HGNC:9076 PLIN1
KEGG Gene (Homo sapiens):5346 PLIN1
Monarch:5346 PLIN1
NCBI Gene:5346 PLIN1
OMIM:170290 PLIN1
UCSC:O60240 PLIN1
Reference Transcript
RefSeq:NM_002666.4 PLIN1
RefSeq:XM_005254934.4 PLIN1
RefSeq:NM_001145311.1 PLIN1
Other Identifiers
11744311_a_at
11758374_s_at
16813173
205913_PM_at
205913_at
3638547
3638548
3638549
3638550
3638551
3638553
3638554
3638555
3638556
3638557
3638558
3638560
3638561
3638562
3638563
3638564
3638565
37122_at
5346
7991313
A_23_P26154
GE53123
GO:0005515
GO:0005783
GO:0005811
GO:0005829
GO:0006629
GO:0008289
GO:0016042
GO:0043226
GO:0070417
HMNXSV003009710
ILMN_1665562
PH_hs_0031487
TC15001834.hg
g4505884_3p_at
Participates
as an input of
phosphorylated perilipin + H2O -> perilipin + orthophosphate (Homo sapiens)
as an output of
perilipin + 2 ATP -> phosphorylated perilipin + 2 ADP (Homo sapiens)
Other forms of this molecule
PLIN1 [lipid droplet]
Modified Residues
Name
O-phospho-L-serine at 81
Coordinate
81
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 277
Coordinate
277
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_001138783.1
,
NP_002657.3
,
XP_005254991.1
OpenTargets
ENSG00000166819
HPA
ENSG00000166819-PLIN1
GeneCards
O60240
Ensembl
ENSG00000166819
,
ENST00000300055
,
ENSP00000402167
,
ENST00000430628
,
ENSP00000300055
PRO
O60240
Pharos - Targets
O60240
Orphanet
20459
HMDB Protein
HMDBP02663
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O14520 AQP7
1
AQP7 [plasma membrane]
(R-HSA-381264)
0.571
4
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