PPP1CA [cytosol]

Stable Identifier
R-HSA-163525
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
PP1CA, Serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit , PP-1A
Locations in the PathwayBrowser for interactor UniProt:O14727 APAF1
Expand all
External Reference Information
External Reference
UniProt:P62136 PPP1CA
Gene Names
PPP1CA, PPP1A
Chain
initiator methionine:1, chain:2-330
Reference Genes
BioGPS Gene:5499 PPP1CA
COSMIC (genes):PPP1CA PPP1CA
CTD Gene:5499 PPP1CA
dbSNP Gene:5499 PPP1CA
ENSEMBL:ENSG00000172531 PPP1CA
HGNC:9281 PPP1CA
KEGG Gene (Homo sapiens):5499 PPP1CA
Monarch:5499 PPP1CA
NCBI Gene:5499 PPP1CA
OMIM:176875 PPP1CA
UCSC:P62136 PPP1CA
Reference Transcript
Other Identifiers
0006290129
04658+3.1.3.16
04660+3.1.3.16
05235+3.1.3.16
11737907_s_at
11754633_x_at
16740977
200846_s_at
32157_at
3378791
3378792
3378794
3378795
3378797
3378799
3378800
3378801
3378802
3378804
3378805
3E7A
3E7B
3EGG
3EGH
3HVQ
3N5U
3V4Y
4545
46833
4G9J
4MOV
4MOY
4MP0
4XPN
5499
5IOH
6ALZ
6CZO
6DNO
6G0I
6G0J
6GHM
74577_s_at
7949765
954_s_at
A0A140VJS9
A_23_P323227
A_23_P434710
AAA36475
AAA36508
AAB26015
AAH01888
AAH04482
AAH08010
AAP35275
AEE61066
AK313586
AP003419
BAG36355
BC001888
BC004482
BC008010
BT006629
CAA50197
CAB004545
CCDS31618
CCDS8160
CCDS8161
E9PMD7
ENSG00000172531
ENSP00000326031
ENSP00000350974
ENSP00000365936
ENST00000312989
ENST00000312989.11
ENST00000358239
ENST00000358239.8
ENST00000376745
ENST00000376745.8
EntrezGene:5499
EntrezGene:PPP1CA
F5H037
F5H1L6
g4506002_3p_a_at
GE79535
GO:0000164
GO:0000228
GO:0000784
GO:0003674
GO:0004721
GO:0004722
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005694
GO:0005730
GO:0005737
GO:0005829
GO:0005886
GO:0005913
GO:0005975
GO:0005977
GO:0005979
GO:0005981
GO:0006091
GO:0006412
GO:0006464
GO:0006470
GO:0006950
GO:0007049
GO:0007155
GO:0007165
GO:0007267
GO:0008150
GO:0008157
GO:0008219
GO:0009056
GO:0009058
GO:0010288
GO:0016032
GO:0016311
GO:0016787
GO:0016791
GO:0019899
GO:0030324
GO:0032091
GO:0032922
GO:0032991
GO:0034641
GO:0035970
GO:0036496
GO:0042587
GO:0042752
GO:0043005
GO:0043021
GO:0043025
GO:0043153
GO:0043167
GO:0043197
GO:0043204
GO:0043226
GO:0044281
GO:0044403
GO:0044877
GO:0046872
GO:0048754
GO:0048856
GO:0051301
GO:0060828
GO:0070062
GO:0070262
GO:0072357
GO:0098609
GO:0098641
GO:0098793
GO:0098794
GO:0098978
GO:1904886
GO:2001241
HGNC:9281
HM005468
HPA046833
ILMN_1695827
ILMN_2377980
IPR004843
IPR006186
IPR029052
IPR031675
J04759
M63960
MIM:176875
NM_001008709
NM_002708
NM_206873
NP_001008709
NP_002699
NP_996756
PF00149
PF16891
PH_hs_0010846
PPP1CA
PPP1CA-201
PPP1CA-202
PPP1CA-203
PR00114
S57501
SM00156
TC11001981.hg
UPI0000000C37
UPI0000070A42
UPI00001FAD56
X70848
Participant Of
input
hasComponent
hasMember
Inferred To
PPP1CA [cytosol] (Bos taurus)
PPP1CA [cytosol] (Danio rerio)
PPP1CA [cytosol] (Gallus gallus)
PPP1CA [cytosol] (Rattus norvegicus)
PPP1CA [cytosol] (Xenopus tropicalis)
Cross References
RefSeq
OpenTargets
GeneCards
ZINC target
PRO
HMDB Protein
PDB
Interactors (115)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P41236 IPP2      0.949 12
 UniProt:Q96KQ4 PPP1R13B  1 0.924 10
 UniProt:Q12972 PP1R8      0.904 8
 UniProt:Q8WUF5 PPP1R13L  1 0.892 9
 UniProt:Q9H175 CSRN2      0.878 9
 UniProt:Q13625 TP53BP2  1 0.86 9
 UniProt:Q96SB3 NEB2      0.857 6
 UniProt:Q15435 PP1R7      0.84 8
 UniProt:Q96S65 CSRN1      0.818 7
 UniProt:P36873 PPP1CC  1 0.814 7
 UniProt:O35274 NEB2      0.813 8
 UniProt:Q9Y2W2 WBP11  1 0.796 5
 UniProt:O75864 PPR37      0.789 5
 UniProt:Q5SWA1 PR15B      0.778 5
 UniProt:P06400 RB1  3 0.771 5
 UniProt:Q6NYC8 PPR18      0.768 5
 UniProt:Q5UIP0 RIF1  1 0.765 5
 UniProt:Q9NWS0 PIHD1      0.76 5
 UniProt:P13807 GYS1  3 0.76 5
 UniProt:Q9NUG6 PDRG1      0.76 5
 UniProt:O60927 PP1RB      0.76 5
 UniProt:Q9UBK9 UXT  1 0.76 5
 UniProt:Q96MX6 WDR92      0.76 5
 UniProt:P19388 POLR2E  2 0.76 5
 UniProt:Q6PJW8 CNST      0.737 4
 UniProt:Q7Z699 SPRED1  2 0.737 4
 UniProt:Q8NI77 KIF18A  1 0.73 4
 UniProt:Q9UQK1 PPP1R3C  2 0.712 4
 UniProt:Q96QC0 PP1RA      0.702 4
 UniProt:Q6NXS1 IPP2B      0.696 5
 UniProt:Q12972-1 PPP1R8      0.693 6
 UniProt:Q86WC6 PPR27      0.691 6
 UniProt:Q9H6T3 RPAP3      0.69 4
 UniProt:O94763 RMP      0.69 4
 UniProt:Q14684 RRP1B      0.667 3
 UniProt:Q6ZMQ8 LMTK1      0.667 3
 UniProt:O95685 PPR3D      0.659 3
 UniProt:Q8TEC5 SH3R2      0.658 3
 UniProt:Q7Z5V6 PPR32      0.658 3
 UniProt:Q9H788 SH24A      0.656 3
 UniProt:Q5S007 LRRK2  1 0.65 6
 UniProt:P46937 YAP1  7 0.643 3
 UniProt:P62140 PPP1CB  2 0.638 3
 UniProt:Q9GZN8 CT027      0.638 3
 UniProt:Q96T49 PP16B      0.621 3
 UniProt:Q86XI6 PPR3B      0.621 3
 UniProt:Q4KMQ1-2 TPRN      0.621 3
 UniProt:Q12972-2 PPP1R8      0.621 5
 UniProt:O35867 NEB1      0.618 3
 UniProt:P49750 YLPM1      0.613 3
 UniProt:O75807 PPP1R15A  1 0.613 5
 UniProt:Q4KMQ1 TPRN      0.613 3
 UniProt:Q8NHQ8 RASF8      0.597 3
 UniProt:Q15834 CC85B      0.597 3
 UniProt:Q9Y265 RUVBL1  1 0.597 3
 UniProt:Q9H792 PEAK1      0.597 3
 UniProt:O14802 POLR3A  2 0.597 3
 UniProt:Q02833 RASF7      0.597 3
 UniProt:A6NKD9 CC85C      0.597 3
 UniProt:Q5T8A7 PPR26      0.592 2
 UniProt:O00566 MPHOSPH10  1 0.592 2
 UniProt:Q8NG31 KNL1  2 0.592 2
 UniProt:O95400 CD2BP2  1 0.592 2
 UniProt:Q9HCH5 SYTL2      0.592 2
 UniProt:Q99459 CDC5L  1 0.59 2
 UniProt:Q5JTV8 TOIP1      0.573 2
 UniProt:P31749 AKT1  13 0.571 4
 UniProt:Q80W00 PP1RA      0.564 2
 UniProt:O95793 STAU1      0.553 2
 UniProt:Q96S59 RANBP9  1 0.553 2
 UniProt:O95405 ZFYVE9      0.553 3
 UniProt:Q96KR7 PHAR3      0.547 2
 UniProt:Q7Z3T8 ZFYVE16  1 0.547 2
 UniProt:Q9H7J1 PPR3E      0.547 2
 UniProt:Q9UPR0 PLCL2      0.547 2
 UniProt:Q8TEP8 CEP192  1 0.544 2
 UniProt:Q14C87 T132D      0.544 2
 UniProt:P49815 TSC2  4 0.544 2
 UniProt:Q9NX63 CHCHD3  3 0.544 2
 UniProt:Q9H4A3 WNK1  1 0.544 2
 UniProt:Q9HBF4 ZFYV1      0.544 2
 UniProt:Q92796 DLG3  2 0.544 2
 UniProt:Q8TEL6 TRPC4AP  1 0.544 2
 UniProt:A8K8P3 SFI1  1 0.544 2
 UniProt:P55199 ELL  1 0.544 2
 UniProt:P16989 YBOX3      0.537 3
 UniProt:P49790 NUP153  1 0.527 2
 UniProt:P09622 DLD  1 0.527 2
 UniProt:Q9ULJ8 NEB1      0.527 2
 UniProt:P60484 PTEN  122 0.524 2
 UniProt:P12830 CDH1  10 0.524 2
 UniProt:O14727 APAF1  4 0.524 2
 UniProt:P63208 SKP1  2 0.524 3
 UniProt:O15169 AXIN1  11 0.524 4
 UniProt:P38398 BRCA1  5 0.524 2
 UniProt:P61962 DCAF7  2 0.508 2
 UniProt:Q15691 MAPRE1  1 0.508 2
 UniProt:O08785 Clock  2 0.508 2
 UniProt:O60828 PQBP1  1 0.508 2
 UniProt:P36313 ICP34      0.508 4
 UniProt:Q76TK5 Q76TK5      0.499 2
 UniProt:P55072 VCP  8 0.499 2
 UniProt:Q05BL1 Q05BL1      0.488 2
 UniProt:O14990 IPP2C      0.488 2
 UniProt:Q9NVI7 ATD3A      0.462 2
 UniProt:Q9UHV9 PFDN2  1 0.462 2
 UniProt:P40227 CCT6A  1 0.462 2
 UniProt:Q6UXN9 WDR82      0.462 2
 UniProt:O94842 TOX4      0.462 2
 UniProt:O15212 PFDN6  1 0.462 2
 UniProt:Q8TEW0 PARD3  3 0.462 2
 UniProt:Q8IWX8 CHERP  1 0.462 2
 UniProt:Q562F6 SGO2  1 0.462 4
 UniProt:Q9Y230 RUVBL2  1 0.462 2
 UniProt:Q96RT1 ERBIN  1 0.462 2