AMBRA1 binds DYNLL1,DYNLL2

Stable Identifier
R-HSA-1632843
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Activating molecule in BECN1-regulated autophagy protein 1 (AMBRA1) is anchored to microtubules through an interaction with dynein light chains 1 and 2, components of the dynein motor complex (Di Bartolomeo et al. 2010, Fimia et al. 2011).

Literature References
PubMed ID Title Journal Year
20921139 The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy

Di Bartolomeo, S, Corazzari, M, Nazio, F, Oliverio, S, Lisi, G, Antonioli, M, Pagliarini, V, Matteoni, S, Fuoco, C, Giunta, L, D'Amelio, M, Nardacci, R, Romagnoli, A, Piacentini, M, Cecconi, F, Fimia, GM

J Cell Biol 2010
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Orthologous Events
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