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POLRMT [mitochondrial matrix]
Stable Identifier
R-HSA-163267
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Icon
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Transcription from mitochondrial promoters (Homo sapiens)
Mitochondrial transcription initiation (Homo sapiens)
Association of TFAM:mt promoter complex with POLRMT:TFB2M (Homo sapiens)
POLRMT:TFB2M complex [mitochondrial matrix] (Homo sapiens)
POLRMT [mitochondrial matrix] (Homo sapiens)
POLRMT:TFB2M:TFAM:mitochondrial promoter complex [mitochondrial matrix] (Homo sapiens)
POLRMT:TFB2M complex [mitochondrial matrix] (Homo sapiens)
POLRMT [mitochondrial matrix] (Homo sapiens)
Organelle biogenesis and maintenance (Homo sapiens)
Mitochondrial biogenesis (Homo sapiens)
Transcriptional activation of mitochondrial biogenesis (Homo sapiens)
Expression of POLRMT (Homo sapiens)
POLRMT [mitochondrial matrix] (Homo sapiens)
External Reference Information
External Reference
UniProt:O00411 POLRMT
Gene Names
POLRMT
Chain
transit peptide:1-41, chain:42-1230
Reference Genes
BioGPS Gene:5442 POLRMT
COSMIC (genes):POLRMT POLRMT
CTD Gene:5442 POLRMT
dbSNP Gene:5442 POLRMT
ENSEMBL:ENSG00000099821.14 POLRMT
HGNC:9200 POLRMT
KEGG Gene (Homo sapiens):5442 POLRMT
Monarch:5442 POLRMT
NCBI Gene:5442 POLRMT
OMIM:601778 POLRMT
UCSC:O00411 POLRMT
Reference Transcript
RefSeq:NM_005035.3 POLRMT
Other Identifiers
0004670446
11724889_a_at
11724890_x_at
11724891_s_at
16866456
17121810
203782_PM_s_at
203782_s_at
203783_PM_x_at
203783_x_at
3765796
3765798
3765800
3765801
3765803
3765804
3765805
3765806
3765809
3765811
3765812
3765813
3765814
3765815
3765817
3765818
3765820
3844657
3844658
3844659
3844660
3844661
3844663
3844665
3844667
3844669
3844670
3844671
3844672
3844675
3844678
3844679
3844680
3844682
3844683
3844684
3844685
3844686
3844687
3844688
3844689
3844690
3844691
3844692
3844694
3844695
3853636
3853648
3853652
40232_at
5442
8032057
A_23_P131096
GE59398
GE86681
GO:0000175
GO:0000428
GO:0001018
GO:0003677
GO:0003723
GO:0003899
GO:0005515
GO:0005622
GO:0005737
GO:0005739
GO:0005759
GO:0006351
GO:0006390
GO:0006391
GO:0016740
GO:0016779
GO:0016787
GO:0032991
GO:0034245
GO:0042645
GO:0043226
GO:0043565
GO:0090503
GO:0140053
GO:0140098
HMNXSV003015487
Hs.153880.0.S1_3p_a_at
ILMN_1770356
TC19000987.hg
U75370_at
g4826925_3p_a_at
Participates
as an output of
Expression of POLRMT (Homo sapiens)
as a component of
POLRMT:TFB2M complex [mitochondrial matrix] (Homo sapiens)
Inferred To
rpo41 [mitochondrial matrix]
(Schizosaccharomyces pombe)
Polrmt [mitochondrial matrix]
(Mus musculus)
Polrmt [mitochondrial matrix]
(Rattus norvegicus)
rpmA [mitochondrial matrix]
(Dictyostelium discoideum)
PolrMT [mitochondrial matrix]
(Drosophila melanogaster)
POLRMT [mitochondrial matrix]
(Bos taurus)
POLRMT [mitochondrial matrix]
(Canis familiaris)
POLRMT [mitochondrial matrix]
(Danio rerio)
POLRMT [mitochondrial matrix]
(Gallus gallus)
POLRMT [mitochondrial matrix]
(Plasmodium falciparum)
POLRMT [mitochondrial matrix]
(Sus scrofa)
RPO41 [mitochondrial matrix]
(Saccharomyces cerevisiae)
Cross References
RefSeq
NP_005026.3
OpenTargets
ENSG00000099821
IntEnz
2.7.7.6
GeneCards
O00411
HPA
ENSG00000099821-POLRMT
Ensembl
ENST00000588649
,
ENSG00000099821
,
ENSP00000465759
PRO
O00411
Pharos - Targets
O00411
Orphanet
25188
HMDB Protein
HMDBP00742
PDB
5OLA
,
6ERQ
,
7A8P
,
4BOC
,
3SPA
,
6ERP
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P52815 MRPL12
1
MRPL12 [mitochondrial inner membrane]
(R-HSA-5368256)
0.677
5
UniProt:Q9H5Q4 TFB2M
1
TFB2M [mitochondrial matrix]
(R-HSA-163272)
0.669
3
UniProt:Q00059 TFAM
2
TFAM [mitochondrial matrix]
(R-HSA-163312)
TFAM(1-246) [cytosol]
(R-HSA-1592203)
0.564
2
UniProt:P25963 NFKBIA
11
PolyUb-NFKBIA [cytosol]
(R-HSA-6782960)
monoSUMO1-K21-NFKBIA [nucleoplasm]
(R-HSA-4656935)
NFKBIA [nucleoplasm]
(R-HSA-4656929)
NFKBIA [cytosol]
(R-HSA-168151)
p-S32,S36-NFKBIA [cytosol]
(R-HSA-177677)
Ub-K21,22-p-S32,S36-NFKBIA [cytosol]
(R-HSA-1168581)
K48PolyUb-K21,22-p-S32,S36-IkBA [cytosol]
(R-HSA-5607659)
Ub-K21,22-p-S32,S36-NFKBIA [cytosol]
(R-HSA-9711050)
NFKBIA S32I [cytosol]
(R-HSA-5228846)
NFKBIA F2_M37del [cytosol]
(R-HSA-9630119)
NFKBIA M37K [cytosol]
(R-HSA-5228805)
0.564
2
UniProt:Q96QE5 TEFM
0.558
6
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