Reactome | ENPP7 [plasma membrane]

ENPP7 [plasma membrane]

Stable Identifier

R-HSA-1631583

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Ectonucleotide pyrophosphatase/phosphodiesterase family member 7, ENPP7_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q6UWV6 ENPP7

Gene Names

ENPP7, UNQ3077/PRO9912

Chain

signal peptide:1-21, chain:22-458

Reference Genes

BioGPS Gene:339221 ENPP7

COSMIC (genes):ENPP7 ENPP7

CTD Gene:339221 ENPP7

dbSNP Gene:339221 ENPP7

ENSEMBL:ENSG00000182156 ENPP7

ENSEMBL_homo_sapiens_GENE:ENSG00000182156.10 ENPP7

HGNC:23764 ENPP7

KEGG Gene (Homo sapiens):339221 ENPP7

Monarch:339221 ENPP7

NCBI Gene:339221 ENPP7

OMIM:616997 ENPP7

UCSC:Q6UWV6 ENPP7

Reference Transcript

RefSeq:NM_178543.4 ENPP7

Other Identifiers

11730150_at

16838457

238245_PM_at

238245_at

339221

3658406

3658407

3689252

3689253

3736966

3736967

3736968

3736969

3736970

3736971

3736972

3736975

3736976

3736977

3736978

8010313

80974_at

A_14_P133008

A_23_P10640

A_33_P3383491

GE88231

GO:0003824

GO:0004767

GO:0005515

GO:0005794

GO:0005886

GO:0005902

GO:0006260

GO:0006629

GO:0006684

GO:0008081

GO:0008156

GO:0008270

GO:0008285

GO:0016020

GO:0016787

GO:0022600

GO:0043226

GO:0044241

GO:0045797

GO:0046479

GO:0046872

GO:0055089

GO:1901135

GO:1904729

GO:2000304

GO:2000755

HMNXSV003010168

Hs.114084.0.A1_3p_at

ILMN_1675413

ILMN_2130468

PH_hs_0006266

TC17000910.hg

Inferred To

NPP1 [plasma membrane] (Saccharomyces cerevisiae)

ENPP7 [plasma membrane] (Bos taurus)

ENPP7 [plasma membrane] (Caenorhabditis elegans)

ENPP7 [plasma membrane] (Canis familiaris)

ENPP7 [plasma membrane] (Dictyostelium discoideum)

ENPP7 [plasma membrane] (Gallus gallus)

ENPP7 [plasma membrane] (Mus musculus)

ENPP7 [plasma membrane] (Rattus norvegicus)

ENPP7 [plasma membrane] (Schizosaccharomyces pombe)

ENPP7 [plasma membrane] (Sus scrofa)

Homologues of ENPP7 [plasma membrane] (Saccharomyces cerevisiae)

NPP2 [plasma membrane] (Saccharomyces cerevisiae)

enpp7 [plasma membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_848638.3

OpenTargets

ENSG00000182156

IntEnz

3.1.4.12

HPA

ENSG00000182156-ENPP7

GeneCards

Q6UWV6

Ensembl

ENSP00000332656, ENSG00000182156, ENST00000328313

PRO

Q6UWV6

Pharos - Targets

Q6UWV6

HMDB Protein

HMDBP01089

PDB

5TCD, 5UDY

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5JR59-3 MTUS2			0.556	3
UniProt:Q9BYV9 BACH2			0.556	3
UniProt:Q5JTD7 LRC73			0.556	3
UniProt:P26371 KRTAP5-9	1	KRTAP5-9 [cytosol] (R-HSA-6810265)	0.556	3
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.556	3
UniProt:Q13509 TUBB3	6	TUBB3 folding intermediate [cytosol] (R-HSA-392806) TUBB3 unfolded [cytosol] (R-HSA-392770) Polyglycyl-TUBB3 [cytosol] (R-HSA-8867372) Polyglutamyl-TUBB3 [cytosol] (R-HSA-8867464) TUBB3 [axonemal microtubule] (R-HSA-5610436) TUBB3 [cytosol] (R-HSA-190532)	0.527	2
UniProt:Q9H4B7 TUBB1	6	TUBB1 folding intermediate [cytosol] (R-HSA-392793) TUBB1 unfolded [cytosol] (R-HSA-392782) Polyglycyl-TUBB1 [cytosol] (R-HSA-8867450) Polyglutamyl-TUBB1 [cytosol] (R-HSA-8867413) TUBB1 [axonemal microtubule] (R-HSA-5610437) TUBB1 [cytosol] (R-HSA-191703)	0.527	2
UniProt:Q9UM22 EPDR1			0.527	2
UniProt:Q96RQ1 ERGI2			0.527	3

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