Reactome | ETS2 [nucleoplasm]

ETS2 [nucleoplasm]

Stable Identifier

R-HSA-1629811

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Protein C-ets-2

Locations in the PathwayBrowser for interactor UniProt:P17612 PRKACA

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External Reference Information

External Reference

UniProt:P15036 ETS2

Gene Names

ETS2

Chain

chain:1-469

Reference Genes

BioGPS Gene:2114 ETS2

COSMIC (genes):ETS2 ETS2

CTD Gene:2114 ETS2

dbSNP Gene:2114 ETS2

ENSEMBL:ENSG00000157557 ETS2

HGNC:3489 ETS2

KEGG:hsa:2114 ETS2

Monarch:2114 ETS2

NCBI Gene:2114 ETS2

OMIM:164740 ETS2

UCSC:P15036 ETS2

Reference Transcript

Other Identifiers

11742752_a_at

11758370_s_at

1519_at

16922779

201328_PM_at

201328_at

201329_PM_s_at

201329_s_at

2114

38739_at

3921078

3921079

3921080

3921081

3921082

3921083

3921084

3921085

3921086

3921087

3921088

3921089

3921090

3921091

3921092

3921093

3921098

3921100

3921101

3921102

3921105

3921107

3921108

3921109

3921110

3921112

3921115

3921116

3921117

3921118

3921119

3921120

8068593

A_14_P117113

A_23_P257924

A_24_P314179

A_24_P382661

GE489366

GE54144

GE79512

GE88270

GO:0000122

GO:0000785

GO:0000977

GO:0000978

GO:0000981

GO:0001227

GO:0001501

GO:0001712

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005829

GO:0005886

GO:0006355

GO:0006357

GO:0007498

GO:0019904

GO:0030154

GO:0035259

GO:0043565

GO:0045944

GO:0048856

GO:0061629

GO:0090009

GO:1990837

HMNXSV003039575

Hs.85146.0.A2_3p_at

ILMN_1720158

J04102_at

PH_hs_0023540

TC21000169.hg

g4885220_3p_a_at

Participates

as an output of

ERF inhibits ETS2 expression (Homo sapiens)

as a member of

ETS1/ETS2 [nucleoplasm] (Homo sapiens)

Other forms of this molecule

p-T72-ETS2 [nucleoplasm]

Inferred To

Ets2 [nucleoplasm] (Mus musculus)

Ets2 [nucleoplasm] (Rattus norvegicus)

pnt [nucleoplasm] (Drosophila melanogaster)

ETS2 [nucleoplasm] (Bos taurus)

ETS2 [nucleoplasm] (Canis familiaris)

ETS2 [nucleoplasm] (Gallus gallus)

ETS2 [nucleoplasm] (Sus scrofa)

ets2 [nucleoplasm] (Danio rerio)

ets2 [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

XP_005260992.1, XP_016883779.1, XP_054180345.1, NP_005230.1

OpenTargets

ENSG00000157557

ENSEMBL

ENSP00000354194, ENST00000653642, ENST00000360938, ENSP00000353344, ENSP00000499226, ENSP00000499775, ENSG00000157557, ENSP00000499315, ENST00000360214, ENST00000662305, ENST00000666778

HPA

ENSG00000157557-ETS2

GeneCards

ETS2

PRO

P15036

Pharos - Targets

P15036

PDB

4BQA, 4MHV

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04637 TP53	20	Unfolded TP53 [cytosol] (R-HSA-6813797) TP53 [cytosol] (R-HSA-8869337) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) polySUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) TP53 F341C [nucleoplasm] (R-HSA-9726318) TP53 G334V [nucleoplasm] (R-HSA-9726126) TP53 L330H [nucleoplasm] (R-HSA-9726124) TP53 A347T [nucleoplasm] (R-HSA-9726339) TP53 R337C [nucleoplasm] (R-HSA-9726118) TP53 L344P [nucleoplasm] (R-HSA-9726075) TP53 L344R [nucleoplasm] (R-HSA-9726073) TP53 R337H [nucleoplasm] (R-HSA-9726169) TP53 R337P [nucleoplasm] (R-HSA-9726168) TP53 L330P [nucleoplasm] (R-HSA-9726136) TP53 L348S [nucleoplasm] (R-HSA-9726366) TP53 R337L [nucleoplasm] (R-HSA-9726163) TP53 K351E [nucleoplasm] (R-HSA-9726258) TP53 F338I [nucleoplasm] (R-HSA-9726358) TP53 R342P [nucleoplasm] (R-HSA-9726101) TP53 L330R [nucleoplasm] (R-HSA-9726133)	0.602	4
UniProt:Q8NHY2 COP1	3	p-S387-RFWD2 [nucleoplasm] (R-HSA-349450) RFWD2 [nucleoplasm] (R-HSA-349454) p-S387-RFWD2 [cytosol] (R-HSA-349439)	0.564	2
UniProt:P37173 TGFBR2	9	TGFBR2 [plasma membrane] (R-HSA-170842) NEDD8-K556,K567-TGFBR2 [plasma membrane] (R-HSA-4332222) TGFBR2 K128Sfs35 [cytosol] (R-HSA-3642166) TGFBR2 K128Afs3 [cytosol] (R-HSA-3642173) TGFBR2 R528C [plasma membrane] (R-HSA-3640899) TGFBR2 R528H [plasma membrane] (R-HSA-3640894) TGFBR2 D522N [plasma membrane] (R-HSA-3640907) TGFBR2 E526Q [plasma membrane] (R-HSA-3645770) TGFBR2 Y470D [plasma membrane] (R-HSA-3640905)	0.556	3
IntAct:EBI-25847655 CCSB			0.556	3
UniProt:P50454 SERPINH1	1	SERPINH1 [endoplasmic reticulum lumen] (R-HSA-2127480)	0.556	3
UniProt:P17612 PRKACA	4	PRKACA [cytosol] (R-HSA-57844) PRKACA [nucleoplasm] (R-HSA-111936) PRKACA [ciliary base] (R-HSA-5610402) PRKACA [mitochondrial matrix] (R-HSA-9838291)	0.556	3
UniProt:Q8WVJ9 TWIST2	1	TWIST2 [nucleoplasm] (R-HSA-445444)	0.524	2
UniProt:Q15672 TWIST1	1	TWIST1 [nucleoplasm] (R-HSA-445442)	0.524	2
UniProt:Q15131 CDK10			0.524	2
UniProt:Q16236 NFE2L2	13	p-S40-NFE2L2 [nucleoplasm] (R-HSA-9715109) p-S,T-NFE2L2 [nucleoplasm] (R-HSA-9715110) p-S40-NFE2L2 [cytosol] (R-HSA-8932290) p-S,T-NFE2L2 [cytosol] (R-HSA-8932311) NFE2L2 [cytosol] (R-HSA-201566) p-S,T-18 AcK-NFE2L2 [nucleoplasm] (R-HSA-9760033) p-S40-18 AcK-NFE2L2 [nucleoplasm] (R-HSA-9760018) ub-NFE2L2 [cytosol] (R-HSA-9758077) ub-p-S335, S338,T-NFE2L2 [nucleoplasm] (R-HSA-9762055) ub-p-S40, S335, S338- NFE2L2 [nucleoplasm] (R-HSA-9762058) p-S344, S347,T-NFE2L2 [nucleoplasm] (R-HSA-9762048) p-S40, S344, S347- NFE2L2 [nucleoplasm] (R-HSA-9762050) p-S,T,S558-NFE2L2 [nucleoplasm] (R-HSA-9795736)	0.508	2
UniProt:Q8NHY2-1 COP1			0.462	2

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