N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate

Stable Identifier
R-HSA-162857
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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In the second step of GPI synthesis, N-acetylglucosaminyl-PI is hydrolyzed to yield glucosaminyl-PI and acetate. The phosphatidylinositol (PI) derivatives involved in this reaction are located in the endoplasmic reticulum membrane, as is the PIG-L enzyme that catalyzes it (Sharma et al. 1999; Pottekat and Menon 2004).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
N-acetylglucosaminylphosphatidylinositol deacetylase activity of PIGL [endoplasmic reticulum membrane]
Physical Entity
Activity
Orthologous Events
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Created
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