(ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI

Stable Identifier
Reaction [transition]
Homo sapiens
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Most human GPI anchors have ethanolamine phosphate groups attached to their first and third mannose residues, but GPI anchors with ethanolamine phosphates attached to all three mannose residues have also been identified. Addition of the third ethanolamine phosphate can be catalyzed by a complex of PIG-F and a newly described human protein, GPI7. The donor of the ethanolamine phosphate for this reaction is unknown (Shishioh et al. 2005).

Literature References
PubMed ID Title Journal Year
15632136 GPI7 is the second partner of PIG-F and involved in modification of glycosylphosphatidylinositol

Kinoshita, T, Ashida, H, Ohishi, K, Hong, Y, Maeda, Y, Shishioh, N

J Biol Chem 2005
Catalyst Activity

phosphotransferase activity, for other substituted phosphate groups of PIGF:PIGG [endoplasmic reticulum membrane]

Orthologous Events
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