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LIPE [cytosol]
Stable Identifier
R-HSA-162503
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Hormone Sensitve Lipase, HSL
Icon
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Triglyceride metabolism (Homo sapiens)
Triglyceride catabolism (Homo sapiens)
hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP (Homo sapiens)
LIPE [cytosol] (Homo sapiens)
phosphorylated HSL + H2O -> HSL + orthophosphate (Homo sapiens)
LIPE [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q05469 LIPE
Gene Names
LIPE
Chain
chain:1-1076
Reference Genes
BioGPS Gene:3991 LIPE
COSMIC (genes):LIPE LIPE
CTD Gene:3991 LIPE
dbSNP Gene:3991 LIPE
ENSEMBL:ENSG00000079435 LIPE
ENSEMBL_homo_sapiens_GENE:ENSG00000079435.10 LIPE
HGNC:6621 LIPE
KEGG Gene (Homo sapiens):3991 LIPE
Monarch:3991 LIPE
NCBI Gene:3991 LIPE
OMIM:151750 LIPE
UCSC:Q05469 LIPE
Reference Transcript
RefSeq:XM_017026810.1 LIPE
RefSeq:XM_005258940.3 LIPE
RefSeq:XM_006723218.2 LIPE
RefSeq:NM_005357.3 LIPE
Other Identifiers
11726872_a_at
11726873_at
16872783
208186_PM_s_at
208186_s_at
213855_PM_s_at
213855_s_at
38320_s_at
38321_r_at
3863610
3863611
3863612
3863613
3863614
3863615
3863616
3863617
3863619
3863621
3863622
3863623
3863624
3863625
3863637
3863638
3863639
3991
8037186
A_23_P38876
A_33_P3294986
GE59131
GO:0003824
GO:0004771
GO:0004806
GO:0005515
GO:0005737
GO:0005811
GO:0005829
GO:0005886
GO:0005901
GO:0006468
GO:0006629
GO:0008202
GO:0008203
GO:0016020
GO:0016042
GO:0016298
GO:0016787
GO:0019433
GO:0033878
GO:0036211
GO:0042572
GO:0043226
GO:0046340
GO:0046485
GO:0047372
GO:0047376
GO:0050253
GO:0102258
GO:0102259
HMNXSV003036256
Hs.95351.1.A1_3p_a_at
ILMN_1670693
PH_hs_0027734
TC19001573.hg
U40002_s_at
g4885450_3p_a_at
Participates
as an output of
phosphorylated HSL + H2O -> HSL + orthophosphate (Homo sapiens)
as an input of
hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP (Homo sapiens)
Other forms of this molecule
p-S950,S951-LIPE [lipid droplet]
p-S950,S951-LIPE [cytosol]
LIPE [lipid droplet]
Cross References
RefSeq
XP_005258997.1
,
XP_016882299.1
,
XP_006723281.1
,
NP_005348.2
Guide to Pharmacology - Targets
2593
OpenTargets
ENSG00000079435
ZINC - Substances
LIPS_HUMAN
ZINC target
Q05469
PRO
Q05469
HPA
ENSG00000079435-LIPE
GeneCards
Q05469
Ensembl
ENST00000244289
,
ENSP00000244289
,
ENSG00000079435
Pharos - Targets
Q05469
Orphanet
23483
ZINC - Predictions - Purchasable
LIPS_HUMAN
HMDB Protein
HMDBP00531
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q3SY00 T10IP
0.556
3
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