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CysS-SQRDL(1-450) [mitochondrial inner membrane]
Stable Identifier
R-HSA-1614576
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
SQR-S-SH
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Sulfur amino acid metabolism (Homo sapiens)
Degradation of cysteine and homocysteine (Homo sapiens)
Sulfide oxidation to sulfate (Homo sapiens)
Persulfide sulfur is dioxygenated (Homo sapiens)
CysS-SQRDL(1-450) [mitochondrial inner membrane] (Homo sapiens)
Persulfide sulfur is transferred onto sulfite (Homo sapiens)
CysS-SQRDL(1-450) [mitochondrial inner membrane] (Homo sapiens)
SQR oxidizes sulfide to bound persulfide (Homo sapiens)
CysS-SQRDL(1-450) [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y6N5 SQRDL
Gene Names
SQRDL, CGI-44, SQOR
Chain
transit peptide:1-, chain:-450
Reference Genes
BioGPS Gene:58472 SQRDL
COSMIC (genes):SQOR SQRDL
CTD Gene:58472 SQRDL
dbSNP Gene:58472 SQRDL
ENSEMBL:ENSG00000137767 SQRDL
HGNC:20390 SQRDL
KEGG:hsa:58472 SQRDL
Monarch:58472 SQRDL
NCBI Gene:58472 SQRDL
OMIM:617658 SQRDL
UCSC:Q9Y6N5 SQRDL
Reference Transcript
RefSeq:NM_021199.3 SQRDL
RefSeq:NM_001271213.1 SQRDL
Other Identifiers
11718515_a_at
16800680
217995_PM_at
217995_at
3592512
3592513
3592514
3592515
3592519
3592522
3592523
3592524
3592525
3592526
3592528
3592529
3592530
3592531
3592534
3592535
3592536
3592537
3592542
3592543
46305_at
58472
7983512
A_23_P3221
GE79664
GO:0003824
GO:0005515
GO:0005739
GO:0005743
GO:0006790
GO:0016491
GO:0043226
GO:0048038
GO:0070221
GO:0070224
GO:0071949
GO:0106436
HMNXSV003001729
ILMN_1667199
PH_hs_0025406
PH_hs_0033367
TC15000364.hg
g10864010_3p_at
Participates
as an input of
Persulfide sulfur is transferred onto sulfite (Homo sapiens)
Persulfide sulfur is dioxygenated (Homo sapiens)
as an output of
SQR oxidizes sulfide to bound persulfide (Homo sapiens)
Other forms of this molecule
2xHC-SQRDL(1-450) [mitochondrial inner membrane]
SQRDL(1-450) [mitochondrial inner membrane]
Inferred To
CysS-SQRDL(1-450) [mitochondrial inner membrane]
(Gallus gallus)
CysS-SQRDL(1-450) [mitochondrial inner membrane]
(Mus musculus)
CysS-SQRDL(1-450) [mitochondrial inner membrane]
(Schizosaccharomyces pombe)
Sqor [mitochondrial inner membrane]
(Drosophila melanogaster)
Sqor [mitochondrial inner membrane]
(Rattus norvegicus)
sqrd-1 [mitochondrial inner membrane]
(Caenorhabditis elegans)
SQOR [mitochondrial inner membrane]
(Bos taurus)
SQOR [mitochondrial inner membrane]
(Canis familiaris)
SQOR [mitochondrial inner membrane]
(Sus scrofa)
sqor [mitochondrial inner membrane]
(Danio rerio)
sqor [mitochondrial inner membrane]
(Xenopus tropicalis)
Modified Residues
Name
L-cysteine persulfide at 201
Coordinate
201
PsiMod Name
L-cysteine persulfide
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to L-cysteine persulfide.
Cross References
ENSEMBL
ENST00000568606
,
ENSP00000456019
,
ENST00000260324
,
ENSP00000260324
OpenTargets
ENSG00000137767
HPA
ENSG00000137767-SQOR
PRO
Q9Y6N5
Pharos - Targets
Q9Y6N5
GlyGen
Q9Y6N5
HMDB Protein
HMDBP08291
PDB
6OIB
,
6OIC
,
6MO6
,
6WH6
,
8DHK
,
6MP5
,
6OI6
,
6OI5
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9NP50 SHCAF
0.527
2
UniProt:P01106 MYC
2
MYC [nucleoplasm]
(R-HSA-188379)
PolyUb-MYC [nucleoplasm]
(R-HSA-6783169)
0.527
2
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