Reactome | SUOX [mitochondrial matrix]

SUOX [mitochondrial matrix]

Stable Identifier

R-HSA-1614570

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

sulfite oxidase

Locations in the PathwayBrowser

Expand all

Metabolism (Homo sapiens)

- Metabolism of amino acids and derivatives (Homo sapiens)
  - Sulfur amino acid metabolism (Homo sapiens)
    - Degradation of cysteine and homocysteine (Homo sapiens)
      - Sulfide oxidation to sulfate (Homo sapiens)
        
        Sulfite is oxidized to sulfate (Homo sapiens)
        
        holo-SUOX [mitochondrial matrix] (Homo sapiens)
        
        SUOX [mitochondrial matrix] (Homo sapiens)

External Reference Information

External Reference

UniProt:P51687 SUOX

Gene Names

SUOX

Chain

transit peptide:1-79, chain:80-545

Reference Genes

BioGPS Gene:6821 SUOX

COSMIC (genes):SUOX SUOX

CTD Gene:6821 SUOX

dbSNP Gene:6821 SUOX

ENSEMBL:ENSG00000139531 SUOX

ENSEMBL_homo_sapiens_GENE:ENSG00000139531.13 SUOX

HGNC:11460 SUOX

KEGG Gene (Homo sapiens):6821 SUOX

Monarch:6821 SUOX

NCBI Gene:6821 SUOX

OMIM:606887 SUOX

UCSC:P51687 SUOX

Reference Transcript

Other Identifiers

11721974_a_at

11747004_a_at

1553030_PM_a_at

1553030_a_at

16752343

204067_PM_at

204067_at

2425917

32122_at

3417034

3417185

3417186

3417187

3417188

3417189

3417190

3417191

3417192

3417193

3417194

3417195

3417200

6821

7956097

A_14_P102057

A_23_P150857

GE57716

GO:0003824

GO:0005515

GO:0005739

GO:0005758

GO:0005759

GO:0006790

GO:0008482

GO:0016491

GO:0020037

GO:0030151

GO:0043226

GO:0043546

GO:0046872

HMNXSV003021372

Hs.16340.0.S2_3p_at

Hs2.16340.1.A1_3p_s_at

ILMN_1710682

ILMN_1803745

ILMN_2383455

L31573_at

PH_hs_0001508

TC12000498.hg

Participates

as a component of

holo-SUOX [mitochondrial matrix] (Homo sapiens)

Inferred To

suox [mitochondrial matrix] (Xenopus tropicalis)

suox-1 [mitochondrial matrix] (Caenorhabditis elegans)

SUOX [mitochondrial matrix] (Bos taurus)

SUOX [mitochondrial matrix] (Canis familiaris)

SUOX [mitochondrial matrix] (Dictyostelium discoideum)

SUOX [mitochondrial matrix] (Drosophila melanogaster)

SUOX [mitochondrial matrix] (Gallus gallus)

SUOX [mitochondrial matrix] (Mus musculus)

SUOX [mitochondrial matrix] (Rattus norvegicus)

SUOX [mitochondrial matrix] (Sus scrofa)

Cross References

RefSeq

XP_016875397.1, NP_001027559.1, NP_001027558.1, NP_000447.2, XP_016875396.1

OpenTargets

ENSG00000139531

IntEnz

1.8.3.1

HPA

ENSG00000139531-SUOX

GeneCards

P51687

Ensembl

ENST00000266971, ENST00000548274, ENSP00000450245, ENSP00000377674, ENST00000394109, ENST00000394115, ENSP00000377668, ENST00000550065, ENSG00000139531, ENST00000356124, ENSP00000266971, ENSP00000348440, ENSP00000450264

PRO

P51687

Pharos - Targets

P51687

Orphanet

15571

HMDB Protein

HMDBP01057

PDB

1MJ4

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P40855 PEX19	1	PEX19 [cytosol] (R-HSA-3009036)	0.556	3
UniProt:Q15669 RHOH	1	RHOH [plasma membrane] (R-HSA-194859)	0.556	3
UniProt:P52747 ZNF143	1	ZNF143 [nucleoplasm] (R-HSA-83837)	0.556	3
UniProt:Q96RU7 TRIB3	3	TRIB3 [plasma membrane] (R-HSA-199447) TRIB3 [cytosol] (R-HSA-162411) TRIB3 [nucleoplasm] (R-HSA-9635877)	0.556	3
UniProt:O95429 BAG4	3	BAG4 [cytosol] (R-HSA-5212670) BAG4(1-126)-p-8Y-FGFR1(208-822) fusion [plasma membrane] (R-HSA-8853156) BAG4(1-126)-FGFR1(208-822) fusion [plasma membrane] (R-HSA-8853157)	0.556	3
UniProt:P01189 POMC	12	POMC(138-176) [secretory granule lumen] (R-HSA-378965) POMC(1-241) [secretory granule lumen] (R-HSA-378943) POMC(138-176) R236G [extracellular region] (R-HSA-5603387) POMC(138-176) E79* [extracellular region] (R-HSA-5623539) POMC(138-176) K25* [extracellular region] (R-HSA-5623536) POMC(138-176) [cytosol] (R-HSA-1502544) POMC(77-87) [extracellular region] (R-HSA-388618) POMC(217-234) [extracellular region] (R-HSA-388617) POMC(138-150) [extracellular region] (R-HSA-388593) POMC(138-176) [extracellular region] (R-HSA-388607) POMC(237-267) [extracellular region] (R-HSA-167405) POMC(237-241) [extracellular region] (R-HSA-167407)	0.556	3
UniProt:Q13901 C1D	1	C1D [nucleoplasm] (R-HSA-6791515)	0.556	3
UniProt:Q9H668 STN1	1	STN1 [nucleoplasm] (R-HSA-9668821)	0.556	3
UniProt:Q13352 ITGB3BP	2	ITGB3BP [cytosol] (R-HSA-3006405) ITGB3BP [nucleoplasm] (R-HSA-606325)	0.556	3
UniProt:O15287 FANCG	2	FANCG [nucleoplasm] (R-HSA-419532) FANCG [cytosol] (R-HSA-420788)	0.556	3
UniProt:Q9BXU0 TEX12	1	TEX12 [nucleoplasm] (R-HSA-912441)	0.556	3
UniProt:Q6UWW8 CES3	1	CES3 [cytosol] (R-HSA-8937441)	0.527	2

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