Reactome | OxA-ARSG [endoplasmic reticulum lumen]

OxA-ARSG [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-1614304

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

active ARSG, Arylsulfatase G, ARSG_HUMAN, ARSG

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96EG1 ARSG

Gene Names

ARSG, KIAA1001, UNQ839/PRO1777

Chain

signal peptide:1-16, chain:17-525

Reference Genes

BioGPS Gene:22901 ARSG

COSMIC (genes):ARSG ARSG

CTD Gene:22901 ARSG

dbSNP Gene:22901 ARSG

ENSEMBL:ENSG00000141337 ARSG

ENSEMBL_homo_sapiens_GENE:ENSG00000141337.13 ARSG

HGNC:24102 ARSG

KEGG Gene (Homo sapiens):22901 ARSG

Monarch:22901 ARSG

NCBI Gene:22901 ARSG

OMIM:610008 ARSG

UCSC:Q96EG1 ARSG

Reference Transcript

Other Identifiers

11726921_a_at

1552632_PM_a_at

1552632_a_at

16837308

22901

3732794

3732797

3732798

3732806

3732807

3732808

3732809

3732815

3732819

3732821

3732822

3732823

3732828

3732829

3732830

3732838

3732846

3732853

3732860

3732861

3732862

3732863

3732864

74785_at

8009443

A_14_P113891

A_23_P4161

A_24_P339416

GE81980

GE83966

GO:0003824

GO:0004065

GO:0005576

GO:0005615

GO:0005764

GO:0005773

GO:0005783

GO:0005788

GO:0006790

GO:0008484

GO:0016787

GO:0033889

GO:0043226

GO:0046872

HMNXSV003040167

HMNXSV003041691

HMNXSV003049902

Hs2.279937.1.S1_3p_s_at

ILMN_1720604

PH_hs_0031638

TC17000802.hg

p33476

Participates

as a member of

active ARS [endoplasmic reticulum lumen] (Homo sapiens)

Other forms of this molecule

ARSG [endoplasmic reticulum lumen]

Inferred To

arsg [endoplasmic reticulum lumen] (Danio rerio)

arsg [endoplasmic reticulum lumen] (Xenopus tropicalis)

ARSG [endoplasmic reticulum lumen] (Bos taurus)

ARSG [endoplasmic reticulum lumen] (Canis familiaris)

ARSG [endoplasmic reticulum lumen] (Sus scrofa)

OxA-ARSG [endoplasmic reticulum lumen] (Gallus gallus)

OxA-ARSG [endoplasmic reticulum lumen] (Mus musculus)

OxA-ARSG [endoplasmic reticulum lumen] (Rattus norvegicus)

OxA-ARSG [endoplasmic reticulum lumen] (Schizosaccharomyces pombe)

Modified Residues

Name

L-3-oxoalanine (Ser) at 84

Coordinate

PsiMod Name

L-3-oxoalanine (Ser)

PsiMod Definition

A protein modification that effectively converts an L-serine residue to L-oxoalanine.

Cross References

RefSeq

XP_016879853.1, XP_016879851.1, NP_055775.2, NP_001254656.1, XP_016879854.1, XP_016879850.1, XP_005257227.1, XP_016879852.1

OpenTargets

ENSG00000141337

HPA

ENSG00000141337-ARSG

GeneCards

Q96EG1

Ensembl

ENST00000621439, ENST00000448504, ENSP00000407193, ENSG00000141337, ENSP00000480910

PRO

Q96EG1

Pharos - Targets

Q96EG1

Orphanet

25566

HMDB Protein

HMDBP07458

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P27824 CANX	2	CANX [lumenal side of endoplasmic reticulum membrane] (R-HSA-983091) CANX [endoplasmic reticulum lumen] (R-HSA-195906)	0.527	2
UniProt:P49840 GSK3A	3	GSK3A [cytosol] (R-HSA-198326) p-S21-GSK3A [cytosol] (R-HSA-198352) p-Y279-GSK3A [cytosol] (R-HSA-9635490)	0.527	2
UniProt:Q8NBK3 SUMF1	1	SUMF1 [endoplasmic reticulum lumen] (R-HSA-1614316)	0.527	2