Reactome | OxA-STS [endoplasmic reticulum membrane]

OxA-STS [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-1606833

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

active STS, Steryl-sulfatase, STS_HUMAN, STS

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P08842 STS

Gene Names

STS, ARSC1

Chain

signal peptide:1-21, chain:22-583

Reference Genes

BioGPS Gene:412 STS

COSMIC (genes):STS STS

CTD Gene:412 STS

dbSNP Gene:412 STS

ENSEMBL:ENSG00000101846 STS

HGNC:11425 STS

KEGG:hsa:412 STS

Monarch:412 STS

NCBI Gene:412 STS

OMIM:300747 STS

UCSC:P08842 STS

Reference Transcript

Participates

as a component of

active STS dimer [endoplasmic reticulum membrane] (Homo sapiens)

Other forms of this molecule

OxA-STS [endoplasmic reticulum lumen]

STS [endoplasmic reticulum lumen]

Inferred To

sts [endoplasmic reticulum membrane] (Xenopus tropicalis)

STS [endoplasmic reticulum membrane] (Bos taurus)

STS [endoplasmic reticulum membrane] (Canis familiaris)

STS [endoplasmic reticulum membrane] (Sus scrofa)

OxA-STS [endoplasmic reticulum membrane] (Gallus gallus)

OxA-STS [endoplasmic reticulum membrane] (Mus musculus)

OxA-STS [endoplasmic reticulum membrane] (Rattus norvegicus)

OxA-STS [endoplasmic reticulum membrane] (Schizosaccharomyces pombe)

Modified Residues

Name

L-3-oxoalanine (Ser) at 75

Coordinate

PsiMod Name

L-3-oxoalanine (Ser)

PsiMod Definition

A protein modification that effectively converts an L-serine residue to L-oxoalanine.

Cross References

ZINC - World Drugs

STS_HUMAN

OpenTargets

ENSG00000101846

ZINC - FDA approved

STS_HUMAN

ZINC - Substances

STS_HUMAN

ZINC - Biogenic

STS_HUMAN

ZINC target

P08842

PRO

P08842

PDB

8EG3, 1P49

ZINC - Investigational

STS_HUMAN

ZINC - Metabolites

STS_HUMAN

IntEnz

3.1.6.2

Pharos - Targets

P08842

Orphanet

STS

ZINC - Predictions - Purchasable

STS_HUMAN

HMDB Protein

HMDBP00493

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y6M5 SLC30A1	1	SLC30A1 [plasma membrane] (R-HSA-435361)	0.527	2
UniProt:Q8NBK3 SUMF1	1	SUMF1 [endoplasmic reticulum lumen] (R-HSA-1614316)	0.527	2
UniProt:Q9BYC5 FUT8	1	FUT8 [Golgi membrane] (R-HSA-1028782)	0.527	2
UniProt:P17302 GJA1	7	GJA1 [Golgi-associated vesicle membrane] (R-HSA-190544) GJA1 [plasma membrane] (R-HSA-158058) p-Y265-GJA1 [plasma membrane] (R-HSA-191657) GJA1 [lysosomal membrane] (R-HSA-196173) GJA1 [endoplasmic reticulum membrane] (R-HSA-190654) GJA1 [Golgi membrane] (R-HSA-190649) p-S373-GJA1 [plasma membrane] (R-HSA-9857671)	0.527	2
UniProt:Q07065 CKAP4	7	CKAP4 [endoplasmic reticulum lumen] (R-HSA-8956737) p-CKAP4 [endoplasmic reticulum lumen] (R-HSA-8956926) CKAP4 [azurophil granule membrane] (R-HSA-6799559) CKAP4 [plasma membrane] (R-HSA-5686306) CKAP4 [specific granule membrane] (R-HSA-6799552) PALM-C100-CKAP4 [plasma membrane] (R-HSA-5686280) PALM-C100-CKAP4 [lamellar body] (R-HSA-5686285)	0.527	2

Cite Us!