Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
MMP17(36-?) [Golgi lumen]
Stable Identifier
R-HSA-1604739
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
proMMP17, Matrix metalloproteinase-17, MMP17_HUMAN, MT4-MMP
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
Activation of Matrix Metalloproteinases (Homo sapiens)
Activation of MT-MMPs by FURIN (Homo sapiens)
proMT-MMPs [Golgi lumen] (Homo sapiens)
MMP17(36-?) [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9ULZ9 MMP17
Gene Names
MMP17, MT4MMP
Chain
signal peptide:1-35, propeptide:36-125, chain:126-565, propeptide:566-603
Reference Genes
BioGPS Gene:4326 MMP17
COSMIC (genes):MMP17 MMP17
CTD Gene:4326 MMP17
dbSNP Gene:4326 MMP17
ENSEMBL:ENSG00000198598 MMP17
HGNC:7163 MMP17
KEGG Gene (Homo sapiens):4326 MMP17
Monarch:4326 MMP17
NCBI Gene:4326 MMP17
OMIM:602285 MMP17
UCSC:Q9ULZ9 MMP17
Reference Transcript
RefSeq:XM_011538355.2 MMP17
RefSeq:XM_011538357.2 MMP17
RefSeq:NM_016155.5 MMP17
RefSeq:XM_011538356.2 MMP17
Other Identifiers
11732047_a_at
16759324
206234_s_at
3438483
3438484
3438485
3438492
3438493
3438495
3438496
3438499
3438500
3438503
3438504
3438507
3438508
3438509
3438510
3438511
3438512
35401_s_at
4326
7959946
GE524699
GO:0003674
GO:0004222
GO:0005575
GO:0005576
GO:0005886
GO:0006508
GO:0008047
GO:0008150
GO:0008233
GO:0008237
GO:0008270
GO:0009056
GO:0016020
GO:0016787
GO:0030198
GO:0030234
GO:0030574
GO:0031012
GO:0031225
GO:0043167
GO:0046872
GO:0070006
PH_hs_0027906
TC12001047.hg
X89576_at
g7706618_3p_a_at
Participates
as a candidate of
proMT-MMPs [Golgi lumen] (Homo sapiens)
Other forms of this molecule
MMP17(126-?) [plasma membrane]
MMP17(126-?) [Golgi lumen]
Inferred To
mmp17 [Golgi lumen]
(Xenopus tropicalis)
zmp-1 [Golgi lumen]
(Caenorhabditis elegans)
Mmp17 [Golgi lumen]
(Mus musculus)
Mmp17 [Golgi lumen]
(Rattus norvegicus)
mmp17a [Golgi lumen]
(Danio rerio)
MMP17 [Golgi lumen]
(Bos taurus)
MMP17 [Golgi lumen]
(Canis familiaris)
MMP17 [Golgi lumen]
(Sus scrofa)
Cross References
RefSeq
XP_011536658.1
,
XP_011536659.1
,
NP_057239.4
,
XP_011536657.1
Guide to Pharmacology - Targets
1641
OpenTargets
ENSG00000198598
ZINC - Substances
MMP17_HUMAN
ZINC target
Q9ULZ9
PRO
Q9ULZ9
GlyGen
Q9ULZ9
HPA
ENSG00000198598-MMP17
GeneCards
Q9ULZ9
Ensembl
ENST00000535291
,
ENSG00000198598
,
ENSP00000353767
,
ENST00000360564
,
ENSP00000441106
Pharos - Targets
Q9ULZ9
ZINC - Predictions - Purchasable
MMP17_HUMAN
HMDB Protein
HMDBP07806
© 2022
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text