Following initial activation autoproteolysis occurs at Glu103-Tyr104 (Knauper et al. 1996a,1996b). This is inhibited by endostatin (Nyberg et al. 2003).
Atkinson, SJ, Smith, B, López-Otin, C, Hembry, RM, Knäuper, V, Murphy, G, Will, H, Stanton, H
Smith, B, López-Otin, C, Knight, G, Knäuper, V, Murphy, G
serine-type endopeptidase activity of MMP13 intermediate forms [extracellular region]
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