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NUDT4 [cytosol]
Stable Identifier
R-HSA-1604676
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
DIPP2, KIAA0487, HDCMB47P
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Inositol phosphate metabolism (Homo sapiens)
Synthesis of pyrophosphates in the cytosol (Homo sapiens)
(PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol (Homo sapiens)
NUDT(1) [cytosol] (Homo sapiens)
NUDT4:Mg2+/Mn2+ [cytosol] (Homo sapiens)
NUDT4 [cytosol] (Homo sapiens)
(PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol (Homo sapiens)
NUDT(1) [cytosol] (Homo sapiens)
NUDT4:Mg2+/Mn2+ [cytosol] (Homo sapiens)
NUDT4 [cytosol] (Homo sapiens)
1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Homo sapiens)
NUDT(1) [cytosol] (Homo sapiens)
NUDT4:Mg2+/Mn2+ [cytosol] (Homo sapiens)
NUDT4 [cytosol] (Homo sapiens)
5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Homo sapiens)
NUDT(1) [cytosol] (Homo sapiens)
NUDT4:Mg2+/Mn2+ [cytosol] (Homo sapiens)
NUDT4 [cytosol] (Homo sapiens)
PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol (Homo sapiens)
NUDT4:Mg2+/Mn2+ [cytosol] (Homo sapiens)
NUDT4 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NZJ9 NUDT4
Gene Names
NUDT4, DIPP2, KIAA0487, HDCMB47P
Chain
chain:1-180
Reference Genes
BioGPS Gene:11163 NUDT4
COSMIC (genes):NUDT4 NUDT4
CTD Gene:11163 NUDT4
dbSNP Gene:11163 NUDT4
ENSEMBL:ENSG00000173598 NUDT4
ENSEMBL_homo_sapiens_GENE:ENSG00000173598.14 NUDT4
HGNC:8051 NUDT4
KEGG Gene (Homo sapiens):11163 NUDT4
Monarch:11163 NUDT4
NCBI Gene:11163 NUDT4
OMIM:609229 NUDT4
UCSC:Q9NZJ9 NUDT4
Reference Transcript
RefSeq:NM_001301024.1 NUDT4
RefSeq:XM_011537796.2 NUDT4
RefSeq:NM_001301022.1 NUDT4
RefSeq:XM_011537794.2 NUDT4
RefSeq:NM_019094.5 NUDT4
RefSeq:XM_011537795.2 NUDT4
RefSeq:NM_001301023.1 NUDT4
RefSeq:NM_199040.3 NUDT4
Other Identifiers
11163
11720343_at
11754453_s_at
11757333_s_at
11758559_s_at
206302_PM_s_at
206302_s_at
206303_PM_s_at
206303_s_at
212181_PM_s_at
212181_s_at
212182_PM_at
212182_at
212183_PM_at
212183_at
2432446
2432447
2432448
2432449
2432450
2432451
3426170
3426171
3426172
3426173
3426174
3426185
3426186
3426187
3426190
3426193
3426194
3426195
3426196
3426197
3426198
3426199
3426200
3426207
3426209
3426210
3426212
3832442
39090_at
71758_r_at
7919193
7957536
A_14_P107632
A_23_P2366
A_24_P335263
A_24_P67946
A_32_P117723
GE590193
GO:0000298
GO:0003723
GO:0003824
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0008486
GO:0016462
GO:0016787
GO:0019722
GO:0019935
GO:0023052
GO:0030515
GO:0034431
GO:0034432
GO:0035556
GO:0043226
GO:0046872
GO:0052845
GO:0052848
GO:0055086
GO:0071543
GO:1901135
GO:1901907
GO:1901909
GO:1901911
HMNXSV003058094
Hs.92381.5.A2_3p_a_at
Hs.92381.5.A3_3p_at
Hs.92381.5.A4_3p_at
ILMN_1706378
ILMN_1794976
ILMN_2353997
PH_hs_0027396
PH_hs_0032825
PH_hs_0037896
TC12000724.hg
TC12002516.hg
g10800135_3p_a_at
g7739471_3p_a_at
Participates
as a component of
NUDT4:Mg2+/Mn2+ [cytosol] (Homo sapiens)
Inferred To
NUDT4 [cytosol]
(Bos taurus)
NUDT4 [cytosol]
(Caenorhabditis elegans)
NUDT4 [cytosol]
(Canis familiaris)
NUDT4 [cytosol]
(Dictyostelium discoideum)
NUDT4 [cytosol]
(Gallus gallus)
NUDT4 [cytosol]
(Mus musculus)
NUDT4 [cytosol]
(Rattus norvegicus)
NUDT4 [cytosol]
(Saccharomyces cerevisiae)
NUDT4 [cytosol]
(Schizosaccharomyces pombe)
NUDT4 [cytosol]
(Sus scrofa)
nudt4 [cytosol]
(Xenopus tropicalis)
Aps [cytosol]
(Drosophila melanogaster)
nudt4b [cytosol]
(Danio rerio)
Cross References
RefSeq
XP_011536098.1
,
NP_001287951.1
,
XP_011536096.1
,
NP_001287953.1
,
XP_011536097.1
,
NP_950241.1
,
NP_001287952.1
,
NP_061967.3
OpenTargets
ENSG00000173598
HPA
ENSG00000173598-NUDT4
GeneCards
Q9NZJ9
Ensembl
ENSG00000173598
,
ENST00000337179
,
ENST00000547014
,
ENST00000415493
,
ENSP00000338352
,
ENSP00000448032
,
ENSP00000406612
PRO
Q9NZJ9
Pharos - Targets
Q9NZJ9
PDB
7NNJ
,
5LTU
HMDB Protein
HMDBP08782
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O76024 WFS1
3
WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956747)
p-WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956998)
WFS1 [endoplasmic reticulum membrane]
(R-HSA-535474)
0.556
3
UniProt:P04792 HSBP1
3
HSPB1 [cytosol]
(R-HSA-450563)
p-S15,S78,S82-HSP27 [cytosol]
(R-HSA-5218697)
p-S78,S82 HSPB1 [cytosol]
(R-HSA-5687009)
0.556
3
UniProt:Q14145 KEAP1
3
Ub-KEAP1 [cytosol]
(R-HSA-6782766)
ub-KEAP1 [cytosol]
(R-HSA-9766647)
KEAP1 [cytosol]
(R-HSA-976038)
0.556
3
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
6
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