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MTMR2 [cytosol]
Stable Identifier
R-HSA-1604662
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
KIAA1073
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
PI Metabolism (Homo sapiens)
Synthesis of PIPs at the ER membrane (Homo sapiens)
PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 (Homo sapiens)
MTMR2:SBF1 [endoplasmic reticulum membrane] (Homo sapiens)
MTMR2 [cytosol] (Homo sapiens)
PI3P is dephosphorylated to PI by MTMR2:SBF1 (Homo sapiens)
MTMR2:SBF1 [endoplasmic reticulum membrane] (Homo sapiens)
MTMR2 [cytosol] (Homo sapiens)
SBF1 binds MTMR2 (Homo sapiens)
MTMR2 [cytosol] (Homo sapiens)
MTMR2:SBF1 [endoplasmic reticulum membrane] (Homo sapiens)
MTMR2 [cytosol] (Homo sapiens)
Synthesis of PIPs at the early endosome membrane (Homo sapiens)
MTMR12 binds MTMR2 (Homo sapiens)
MTMR2 [cytosol] (Homo sapiens)
MTMR2:MTMR12 [cytosol] (Homo sapiens)
MTMR2 [cytosol] (Homo sapiens)
MTMR2 binds MTMR10 (Homo sapiens)
MTMR2 [cytosol] (Homo sapiens)
MTMR2:MTMR10 [cytosol] (Homo sapiens)
MTMR2 [cytosol] (Homo sapiens)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Homo sapiens)
MTM1,MTMR2,MTMR4 [cytosol] (Homo sapiens)
MTMR2 [cytosol] (Homo sapiens)
PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane (Homo sapiens)
MTM1,MTMR2,MTMR4 [cytosol] (Homo sapiens)
MTMR2 [cytosol] (Homo sapiens)
Synthesis of PIPs at the late endosome membrane (Homo sapiens)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane (Homo sapiens)
MTM1,MTMR2,MTMR4,MTMR7 [cytosol] (Homo sapiens)
MTMR2 [cytosol] (Homo sapiens)
PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane (Homo sapiens)
MTM1,MTMR2,MTMR4,MTMR7 [cytosol] (Homo sapiens)
MTMR2 [cytosol] (Homo sapiens)
Synthesis of PIPs at the plasma membrane (Homo sapiens)
MTMR2 binds SBF2 (Homo sapiens)
MTMR2 homodimer [cytosol] (Homo sapiens)
MTMR2 [cytosol] (Homo sapiens)
MTMR2:SBF2 Tetramer [cytosol] (Homo sapiens)
MTMR2 homodimer [cytosol] (Homo sapiens)
MTMR2 [cytosol] (Homo sapiens)
MTMR2 dimerizes (Homo sapiens)
MTMR2 [cytosol] (Homo sapiens)
MTMR2 homodimer [cytosol] (Homo sapiens)
MTMR2 [cytosol] (Homo sapiens)
PI(3,5)P2 is dephosphorylated to PI5P by the MTMR2:SBF2 tetramer at the plasma membrane (Homo sapiens)
MTMR2:SBF2 Tetramer [cytosol] (Homo sapiens)
MTMR2 homodimer [cytosol] (Homo sapiens)
MTMR2 [cytosol] (Homo sapiens)
PI3P is dephosphorylated to PI by the MTMR2:SBF2 tetramer at the plasma membrane (Homo sapiens)
MTMR2:SBF2 Tetramer [cytosol] (Homo sapiens)
MTMR2 homodimer [cytosol] (Homo sapiens)
MTMR2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13614 MTMR2
Gene Names
MTMR2, KIAA1073
Chain
chain:1-643
Reference Genes
BioGPS Gene:8898 MTMR2
COSMIC (genes):MTMR2 MTMR2
CTD Gene:8898 MTMR2
dbSNP Gene:8898 MTMR2
ENSEMBL:ENSG00000087053 MTMR2
HGNC:7450 MTMR2
KEGG Gene (Homo sapiens):8898 MTMR2
Monarch:8898 MTMR2
NCBI Gene:8898 MTMR2
OMIM:603557 MTMR2
UCSC:Q13614 MTMR2
Reference Transcript
RefSeq:XM_005274375.2 MTMR2
RefSeq:NM_201278.2 MTMR2
RefSeq:NM_001243571.1 MTMR2
RefSeq:XM_005274374.2 MTMR2
RefSeq:NM_201281.2 MTMR2
RefSeq:NM_016156.5 MTMR2
Other Identifiers
11732292_a_at
11732293_a_at
11736170_a_at
11739550_a_at
16743483
203211_s_at
203212_s_at
214649_s_at
33277_at
3387480
3387482
3387484
3387485
3387486
3387487
3387488
3387489
3387491
3387492
3387496
3387497
3387498
3387499
3387501
3387502
3387503
3387506
3387507
3387512
3387514
3387520
3387525
3387526
3387527
3387528
7951112
8898
A_23_P64019
A_24_P406830
GE61868
GO:0002091
GO:0003674
GO:0004438
GO:0004725
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005737
GO:0005768
GO:0005773
GO:0005774
GO:0005829
GO:0005886
GO:0005975
GO:0006464
GO:0006470
GO:0006629
GO:0006661
GO:0006810
GO:0007165
GO:0007267
GO:0008021
GO:0008138
GO:0008150
GO:0009056
GO:0009058
GO:0010008
GO:0014069
GO:0016020
GO:0016192
GO:0016311
GO:0016787
GO:0016791
GO:0022607
GO:0030154
GO:0030424
GO:0030425
GO:0031410
GO:0031642
GO:0031901
GO:0032288
GO:0034330
GO:0035335
GO:0042802
GO:0042995
GO:0043197
GO:0043226
GO:0043231
GO:0044281
GO:0045806
GO:0046488
GO:0046855
GO:0046856
GO:0048471
GO:0048646
GO:0048666
GO:0048856
GO:0050877
GO:0052629
GO:0052866
GO:0060304
GO:0070062
GO:0090394
GO:0097060
GO:0097062
GO:2000643
GO:2000645
Hs.181326.0.S1_3p_a_at
Hs.278491.0.S2_3p_s_at
ILMN_1659952
ILMN_1898297
ILMN_2351029
PH_hs_0010729
TC11002209.hg
TC11003302.hg
U58033_at
g7705563_3p_a_at
Participant Of
hasComponent
MTMR2 homodimer [cytosol]
MTMR2:MTMR10 [cytosol]
MTMR2:MTMR12 [cytosol]
MTMR2:SBF1 [endoplasmic reticulum membrane]
input
MTMR12 binds MTMR2
MTMR2 binds MTMR10
MTMR2 dimerizes
SBF1 binds MTMR2
hasMember
MTM1,MTMR2,MTMR4 [cytosol]
MTM1,MTMR2,MTMR4,MTMR7 [cytosol]
Inferred To
YMR1 [cytosol] (Saccharomyces cerevisiae)
mtm-1 [cytosol] (Caenorhabditis elegans)
MTMR2 [cytosol] (Canis familiaris)
MTMR2 [cytosol] (Dictyostelium discoideum)
MTMR2 [cytosol] (Gallus gallus)
MTMR2 [cytosol] (Schizosaccharomyces pombe)
MTMR2 [cytosol] (Sus scrofa)
Mtmr2 [cytosol] (Mus musculus)
Mtmr2 [cytosol] (Rattus norvegicus)
Homologues of MTMR2 [cytosol] (Dictyostelium discoideum)
mtmr2 [cytosol] (Danio rerio)
mtmr2 [cytosol] (Xenopus tropicalis)
mtm [cytosol] (Drosophila melanogaster)
pats1 [cytosol] (Dictyostelium discoideum)
Cross References
RefSeq
NP_057240.3
,
XP_005274432.1
,
NP_958435.1
,
NP_001230500.1
,
XP_005274431.1
,
NP_958438.1
OpenTargets
ENSG00000087053
HPA
ENSG00000087053-MTMR2
GeneCards
Q13614
Ensembl
ENSP00000386882
,
ENST00000409459
,
ENSP00000345752
,
ENST00000346299
,
ENST00000393223
,
ENSP00000343737
,
ENSG00000087053
,
ENSP00000376915
,
ENST00000352297
PRO
Q13614
Orphanet
16477
PDB
1M7R
,
1ZVR
,
1ZSQ
,
1LW3
,
5GNH
HMDB Protein
HMDBP11837
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P07196 NEFL
1
NEFL [cytosol]
(R-HSA-432284)
0.508
2
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