Reactome | MTMR1 [cytosol]

MTMR1 [cytosol]

Stable Identifier

R-HSA-1604647

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
  - Signaling by Rho GTPases (Homo sapiens)
    - RHO GTPase cycle (Homo sapiens)
      - RHOF GTPase cycle (Homo sapiens)
        
        RHOF binds effectors at the plasma membrane (Homo sapiens)
        
        RHOF effectors [cytosol] (Homo sapiens)
        
        MTMR1 [cytosol] (Homo sapiens)
        
        RHOF:GTP:RHOF effectors [plasma membrane] (Homo sapiens)
        
        RHOF effectors [cytosol] (Homo sapiens)
        
        MTMR1 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q13613 MTMR1

Gene Names

MTMR1

Chain

chain:1-665

Reference Genes

BioGPS Gene:8776 MTMR1

COSMIC (genes):MTMR1 MTMR1

CTD Gene:8776 MTMR1

dbSNP Gene:8776 MTMR1

ENSEMBL:ENSG00000063601 MTMR1

HGNC:7449 MTMR1

KEGG:hsa:8776 MTMR1

Monarch:8776 MTMR1

NCBI Gene:8776 MTMR1

OMIM:300171 MTMR1

UCSC:Q13613 MTMR1

Reference Transcript

Other Identifiers

11733511_a_at

11733512_s_at

11745335_a_at

11761931_a_at

17107717

213511_3p_s_at

213511_PM_s_at

213511_s_at

214975_PM_s_at

214975_s_at

216095_PM_x_at

216095_x_at

216303_PM_s_at

216303_s_at

34654_at

3994847

3994848

3994849

3994851

3994857

3994861

3994865

3994866

3994867

3994868

3994869

3994870

3994871

3994872

3994874

3994875

3994876

3994877

3994878

3994879

3994882

3994884

3994885

3994886

3994887

3994888

3994889

3994893

3994894

3994895

3994896

3994897

3994898

3994903

8170443

8776

A_14_P101514

A_14_P119856

A_14_P120287

A_24_P290874

A_33_P3327097

GE544158

GE55256

GO:0003824

GO:0004438

GO:0005737

GO:0005829

GO:0005886

GO:0006629

GO:0006661

GO:0016020

GO:0016311

GO:0016787

GO:0042803

GO:0046488

GO:0046856

GO:0052629

GO:0052866

GO:0060304

GO:0106018

HMNXSV003024397

HMNXSV003041038

HMNXSV003049721

Hs.204920.0.S1_3p_s_at

Hs.23200.1.A1_3p_a_at

Hs.23200.1.A1_3p_s_at

Hs.23200.2.A1_3p_s_at

ILMN_1660976

ILMN_1715110

ILMN_1741556

ILMN_1876121

PH_hs_0016735

TC0X000724.hg

U58032_at

Participates

as a candidate of

RHOF effectors [cytosol] (Homo sapiens)

as a member of

MTM1,MTMR1,MTMR3,MTMR6,MTMR14,SYNJ1,SYNJ2 [cytosol] (Homo sapiens)

Inferred To

YMR1 [cytosol] (Saccharomyces cerevisiae)

Homologues of MTMR1 [cytosol] (Caenorhabditis elegans)

Homologues of MTMR1 [cytosol] (Dictyostelium discoideum)

MTMR1 [cytosol] (Bos taurus)

MTMR1 [cytosol] (Caenorhabditis elegans)

MTMR1 [cytosol] (Canis familiaris)

MTMR1 [cytosol] (Danio rerio)

MTMR1 [cytosol] (Dictyostelium discoideum)

MTMR1 [cytosol] (Drosophila melanogaster)

MTMR1 [cytosol] (Gallus gallus)

MTMR1 [cytosol] (Mus musculus)

MTMR1 [cytosol] (Rattus norvegicus)

MTMR1 [cytosol] (Schizosaccharomyces pombe)

MTMR1 [cytosol] (Sus scrofa)

MTMR1 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_003819.1, XP_006724918.1

ENSEMBL

ENSP00000359417, ENST00000370390, ENSP00000434105, ENSG00000063601, ENST00000485376

OpenTargets

ENSG00000063601

GeneCards

MTMR1

HPA

ENSG00000063601-MTMR1

PRO

Q13613

Pharos - Targets

Q13613

GlyGen

Q13613

HMDB Protein

HMDBP11836

PDB

5C16

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13614 MTMR2	1	MTMR2 [cytosol] (R-HSA-1604662)	0.527	3
UniProt:O75496 GMNN	2	GMNN [nucleoplasm] (R-HSA-113554) PolyUb-GMNN [nucleoplasm] (R-HSA-68585)	0.527	2