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ISYNA1 [cytosol]
Stable Identifier
R-HSA-1604599
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
INO1, hIPS
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Inositol phosphate metabolism (Homo sapiens)
Synthesis of IP2, IP, and Ins in the cytosol (Homo sapiens)
Glc6P is isomerised to I3P by ISYNA1 in the cytosol (Homo sapiens)
ISYNA1:NAD+ [cytosol] (Homo sapiens)
ISYNA1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NPH2 ISYNA1
Gene Names
ISYNA1, INO1
Chain
chain:1-558
Reference Genes
BioGPS Gene:51477 ISYNA1
COSMIC (genes):ISYNA1 ISYNA1
CTD Gene:51477 ISYNA1
dbSNP Gene:51477 ISYNA1
ENSEMBL:ENSG00000105655 ISYNA1
ENSEMBL_homo_sapiens_GENE:ENSG00000105655.19 ISYNA1
HGNC:29821 ISYNA1
KEGG Gene (Homo sapiens):51477 ISYNA1
Monarch:51477 ISYNA1
NCBI Gene:51477 ISYNA1
OMIM:611670 ISYNA1
UCSC:Q9NPH2 ISYNA1
Reference Transcript
RefSeq:NM_016368.4 ISYNA1
RefSeq:NM_001253389.1 ISYNA1
RefSeq:NM_001170938.1 ISYNA1
Other Identifiers
11725025_s_at
11749810_s_at
11757371_x_at
16870401
222240_PM_s_at
222240_s_at
228552_PM_s_at
228552_s_at
3779412
3854984
3854985
3854986
3854987
3854988
3854990
3854991
3854993
3854995
3854996
3854998
3854999
3855001
3855003
3855004
3855005
3855006
3855008
3855010
48092_at
49690_at
51477
76665_at
8035465
A_23_P5131
A_33_P3306504
GO:0003824
GO:0004512
GO:0005515
GO:0005737
GO:0005829
GO:0005975
GO:0006021
GO:0006629
GO:0008654
GO:0016853
HMNXSV003006595
Hs.324618.3.A1_3p_a_at
Hs.33713.2.S1_3p_a_at
ILMN_1747934
PH_hs_0019212
TC19001289.hg
Participates
as a component of
ISYNA1:NAD+ [cytosol] (Homo sapiens)
Inferred To
ISYNA1 [cytosol]
(Bos taurus)
ISYNA1 [cytosol]
(Dictyostelium discoideum)
ISYNA1 [cytosol]
(Drosophila melanogaster)
ISYNA1 [cytosol]
(Gallus gallus)
ISYNA1 [cytosol]
(Mus musculus)
ISYNA1 [cytosol]
(Plasmodium falciparum)
ISYNA1 [cytosol]
(Rattus norvegicus)
ISYNA1 [cytosol]
(Saccharomyces cerevisiae)
ISYNA1 [cytosol]
(Sus scrofa)
inos-1 [cytosol]
(Caenorhabditis elegans)
isyna1 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_057452.1
,
NP_001240318.1
,
NP_001164409.1
OpenTargets
ENSG00000105655
GeneCards
Q9NPH2
HPA
ENSG00000105655-ISYNA1
Ensembl
ENSP00000475677
,
ENSG00000105655
,
ENSP00000337746
,
ENST00000338128
,
ENSP00000415458
,
ENST00000457269
,
ENST00000578963
PRO
Q9NPH2
Pharos - Targets
Q9NPH2
HMDB Protein
HMDBP05901
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9NUX5 POT1
1
POT1 [nucleoplasm]
(R-HSA-174890)
0.508
2
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
6
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