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IPPK [cytosol]
Stable Identifier
R-HSA-1604598
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
C9orf12
Locations in the PathwayBrowser for interactor UniProt:Q9H461 FZD8
Expand all
Metabolism (Homo sapiens)
Inositol phosphate metabolism (Homo sapiens)
Synthesis of pyrophosphates in the cytosol (Homo sapiens)
I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Homo sapiens)
IPPK [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H8X2 IPPK
Gene Names
IPPK, C9orf12
Chain
chain:1-491
Reference Genes
BioGPS Gene:64768 IPPK
COSMIC (genes):IPPK IPPK
CTD Gene:64768 IPPK
dbSNP Gene:64768 IPPK
ENSEMBL:ENSG00000127080 IPPK
ENSEMBL_homo_sapiens_GENE:ENSG00000127080.10 IPPK
HGNC:14645 IPPK
KEGG Gene (Homo sapiens):64768 IPPK
Monarch:64768 IPPK
NCBI Gene:64768 IPPK
OMIM:619043 IPPK
UCSC:Q9H8X2 IPPK
Reference Transcript
RefSeq:NM_022755.5 IPPK
Other Identifiers
11729257_at
11757762_s_at
17095918
219092_PM_s_at
219092_s_at
222823_PM_at
222823_at
3214925
3214927
3214928
3214929
3214930
3214931
3214936
3214939
3214940
3214944
3214946
3214947
3214950
3214953
3214954
3214957
3214958
3214963
3214964
3214965
3214966
3504591
64768
65077_at
8162421
88371_at
88374_g_at
A_23_P123582
A_33_P3371514
A_33_P3418120
GE57031
GO:0000166
GO:0003824
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0016301
GO:0016310
GO:0016740
GO:0032958
GO:0035299
GO:0043226
GO:0043647
GO:0060090
GO:1901838
HMNXSV003015320
Hs.16603.0.A2_3p_at
ILMN_1732873
PH_hs_0001532
TC09001339.hg
g12232422_3p_a_at
Other forms of this molecule
IPPK [nucleoplasm]
Inferred To
Ippk [cytosol]
(Mus musculus)
Ippk [cytosol]
(Rattus norvegicus)
IPPK [cytosol]
(Bos taurus)
IPPK [cytosol]
(Canis familiaris)
IPPK [cytosol]
(Gallus gallus)
IPPK [cytosol]
(Sus scrofa)
ippk [cytosol]
(Danio rerio)
ippk [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_073592.1
OpenTargets
ENSG00000127080
IntEnz
2.7.1.158
GeneCards
Q9H8X2
HPA
ENSG00000127080-IPPK
Ensembl
ENST00000287996
,
ENSP00000287996
,
ENSG00000127080
PRO
Q9H8X2
Pharos - Targets
Q9H8X2
HMDB Protein
HMDBP09441
Interactors (56)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q15041 AR6P1
0.527
2
UniProt:Q99717 SMAD5
3
SMAD5 [cytosol]
(R-HSA-201431)
p-S463,S465-SMAD5 [nucleoplasm]
(R-HSA-201432)
p-S463,S465-SMAD5 [cytosol]
(R-HSA-201473)
0.527
2
UniProt:Q9NWS8 RMND1
0.527
2
UniProt:Q9NX40 OCAD1
0.527
2
UniProt:P19634 SLC9A1
1
SLC9A1 [plasma membrane]
(R-HSA-426006)
0.527
2
UniProt:P62341 SELT
0.527
2
UniProt:Q12846 STX4
4
STX4 [phagocytic vesicle membrane]
(R-HSA-2029044)
STX4 [plasma membrane]
(R-HSA-181519)
STX4 [cytosol]
(R-HSA-114505)
p-STX4 [cytosol]
(R-HSA-114681)
0.527
2
UniProt:Q96D05 F241B
0.527
2
UniProt:Q07065 CKAP4
7
CKAP4 [endoplasmic reticulum lumen]
(R-HSA-8956737)
p-CKAP4 [endoplasmic reticulum lumen]
(R-HSA-8956926)
CKAP4 [azurophil granule membrane]
(R-HSA-6799559)
CKAP4 [plasma membrane]
(R-HSA-5686306)
CKAP4 [specific granule membrane]
(R-HSA-6799552)
PALM-C100-CKAP4 [plasma membrane]
(R-HSA-5686280)
PALM-C100-CKAP4 [lamellar body]
(R-HSA-5686285)
0.527
2
UniProt:Q9Y2U8 LEMD3
4
LEMD3 [endosome membrane]
(R-HSA-9715091)
LEMD3 [endoplasmic reticulum membrane]
(R-HSA-9714458)
LEMD3 [plasma membrane]
(R-HSA-9715186)
LEMD3 [nuclear envelope]
(R-HSA-2993886)
0.527
2
UniProt:O75063 XYLK
0.527
2
UniProt:Q06418 TYRO3
0.527
2
UniProt:Q8NBN3 TMEM87A
1
TMEM87A [endoplasmic reticulum membrane]
(R-HSA-9714348)
0.527
2
UniProt:Q5KU26 COLEC12
2
COLEC12 [endocytic vesicle membrane]
(R-HSA-2981044)
COLEC12 [plasma membrane]
(R-HSA-2187209)
0.527
2
UniProt:O43909 EXTL3
1
EXTL3 [endoplasmic reticulum membrane]
(R-HSA-535476)
0.527
2
UniProt:Q9NPR9 GP108
0.527
2
UniProt:O95858 TSPAN15
2
TSPAN15 [plasma membrane]
(R-HSA-9010043)
TSPAN15 [endoplasmic reticulum lumen]
(R-HSA-9010117)
0.527
2
UniProt:Q86VR2 RETR3
0.527
2
UniProt:Q13585 MTR1L
0.527
2
UniProt:Q12770 SCAP
2
SCAP [endoplasmic reticulum membrane]
(R-HSA-1655740)
SCAP [Golgi membrane]
(R-HSA-1655739)
0.527
2
UniProt:Q8WY07 SLC7A3
1
SLC7A3 [plasma membrane]
(R-HSA-375779)
0.527
2
UniProt:Q9Y375 NDUFAF1
1
NDUFAF1 [mitochondrial inner membrane]
(R-HSA-5689050)
0.527
2
UniProt:O75110 ATP9A
1
ATP9A [plasma membrane]
(R-HSA-939754)
0.527
2
UniProt:Q8TBA6 GOLGA5
2
GOLGA5 [transport vesicle]
(R-HSA-8847517)
GOLGA5 [Golgi membrane]
(R-HSA-8847514)
0.527
2
UniProt:Q14571 ITPR2
2
ITPR2 [platelet dense tubular network membrane]
(R-HSA-418281)
ITPR2 [endoplasmic reticulum membrane]
(R-HSA-3006467)
0.527
2
UniProt:Q9NUE0 ZDH18
0.527
2
UniProt:Q8N6G5 CSGALNACT2
1
CSGALNACT2 [Golgi membrane]
(R-HSA-1971506)
0.527
2
UniProt:Q8NHS3 MFSD8
0.527
2
UniProt:Q8N8L6 ARL10
0.527
2
UniProt:Q6Y1H2 HACD2
1
PTPLB [endoplasmic reticulum membrane]
(R-HSA-5676075)
0.527
2
UniProt:Q96BS2 CHP3
0.527
2
UniProt:Q92633 LPAR1
1
LPAR1 [plasma membrane]
(R-HSA-419354)
0.527
2
UniProt:Q8IUH4 ZDH13
0.527
2
UniProt:Q9H461 FZD8
2
ub-FZD8 [plasma membrane]
(R-HSA-4641183)
FZD8 [plasma membrane]
(R-HSA-443947)
0.527
2
UniProt:Q9NZH0 GPC5B
0.527
2
UniProt:Q9HA82 CERS4
1
CERS4 [endoplasmic reticulum membrane]
(R-HSA-428138)
0.527
2
UniProt:Q7Z7B1 PIGW
1
PIGW [endoplasmic reticulum membrane]
(R-HSA-162693)
0.527
2
UniProt:Q9BQ95 ECSIT
2
ECSIT [cytosol]
(R-HSA-168064)
ECSIT [mitochondrial inner membrane]
(R-HSA-5689047)
0.527
2
UniProt:A0PJW6 TMEM223
1
TMEM223 [mitochondrial inner membrane]
(R-HSA-9865797)
0.527
2
UniProt:P17931 LGALS3
3
LGALS3 [ficolin-1-rich granule membrane]
(R-HSA-6803307)
LGALS3 [secretory granule membrane]
(R-HSA-6803327)
LGALS3 [plasma membrane]
(R-HSA-879445)
0.527
2
UniProt:Q8TAD4 SLC30A5
2
SLC30A5 [Golgi membrane]
(R-HSA-9817559)
SLC30A5 [secretory granule membrane]
(R-HSA-437105)
0.527
2
UniProt:O00186 STXBP3
4
p-Y521-STXBP3 [plasma membrane]
(R-HSA-2263472)
STXBP3 [plasma membrane]
(R-HSA-2263473)
p-STXBP3 [cytosol]
(R-HSA-114680)
STXBP3 [cytosol]
(R-HSA-114682)
0.527
2
UniProt:Q9H2C2 ARV1
1
ARV1 [endoplasmic reticulum membrane]
(R-HSA-5216144)
0.527
2
UniProt:P17152 TMEM11
1
TMEM11 [mitochondrial inner membrane]
(R-HSA-8949578)
0.527
2
UniProt:Q9HD23 MRS2
1
MRS2 [mitochondrial inner membrane]
(R-HSA-5216072)
0.527
2
UniProt:O75845 SC5D
1
SC5D [endoplasmic reticulum membrane]
(R-HSA-195662)
0.527
2
UniProt:Q9Y397 ZDHHC9
1
ZDHHC9 [Golgi membrane]
(R-HSA-9647931)
0.527
2
UniProt:Q6ZMG9 CERS6
1
CERS6 [endoplasmic reticulum membrane]
(R-HSA-428145)
0.527
2
UniProt:Q96B77 TMEM186
1
TMEM186 [mitochondrial inner membrane]
(R-HSA-9708009)
0.527
2
UniProt:Q5T3F8 CSCL2
0.527
2
UniProt:Q9Y6X5 ENPP4
2
ENPP4 [plasma membrane]
(R-HSA-6806519)
ENPP4 [ficolin-1-rich granule membrane]
(R-HSA-6801493)
0.527
2
UniProt:Q9NRX5 SERINC1
1
SERINC1 [plasma membrane]
(R-HSA-5215963)
0.527
2
UniProt:Q9UNK0 STX8
0.527
2
UniProt:Q8N6M3 FITM2
1
FITM2 [endoplasmic reticulum membrane]
(R-HSA-8857678)
0.527
2
UniProt:Q7Z7G2 CPLX4
0.527
2
UniProt:Q8N5B7 CERS5
1
CERS5 [endoplasmic reticulum membrane]
(R-HSA-428168)
0.527
2
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