BCR-FGFR1 fusion mutant dimer

Stable Identifier
R-HSA-1604525
Type
Complex
Species
Homo sapiens
Compartment
Synonyms
BCR(1-584)-FGFR1(419-822) fusion dimer, t(8:22) BCR-FGFR1 fusion dimer
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
11739186 The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins

Demiroglu, A, Steer, EJ, Heath, C, Taylor, K, Bentley, M, Allen, SL, Koduru, P, Brody, JP, Hawson, G, Rodwell, R, Doody, ML, Carnicero, F, Reiter, A, Goldman, JM, Melo, JV, Cross, NC

Blood 2001
Participants
Participant Of
Disease
Name Identifier Synonyms
myelodysplastic myeloproliferative cancer 4972 Myeloproliferative/Myelodysplastic syndromes, unclassifiable myelodysplastic myeloproliferative disease, Unclassifiable Myeloproliferative/Myelodysplastic syndrome, Myelodysplastic/myeloproliferative disease (morphologic abnormality)
precursor lymphoblastic lymphoma/leukemia 5600
chronic myeloid leukemia 8552 CML, chronic myelogenous leukemia, no ICD-O subtype (morphologic abnormality), chronic myeloid leukemia, disease (disorder), chronic myeloid leukemia without mention of remission, CML - chronic Myelogenous Leukemia, chronic myeloid leukemia in remission (disorder), Myeloid Leukemia, chronic, CML in Remission, chronic myeloid leukemia in remission, chronic myeloid leukaemia, chronic myeloid leukemia NOS (disorder)