Reactome | DTX2 [cytosol]

DTX2

Stable Identifier

R-HSA-1604436

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Protein deltex-2

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q86UW9 DTX2

Gene Names

DTX2, KIAA1528, RNF58

Chain

chain:1-622

Reference Genes

BioGPS Gene:113878 DTX2

COSMIC (genes):DTX2 DTX2

CTD Gene:113878 DTX2

dbSNP Gene:113878 DTX2

ENSEMBL:ENSG00000091073 DTX2

HGNC:15973 DTX2

KEGG Gene (Homo sapiens):hsa:113878 DTX2

Monarch:113878 DTX2

NCBI Gene:113878 DTX2

OMIM:613141 DTX2

UCSC:Q86UW9 DTX2

Reference Transcript

Other Identifiers

0003190168

113878

11740981_a_at

11755938_a_at

17124592

17124594

17124596

215732_3p_s_at

215732_s_at

37977_at

42931

8133736

A_21_P0013244

A_23_P395033

A_33_P3502640

AAH08856

AAH18555

AAH26059

AAH93079

AAP21881

AAP57518

AAP57519

AAY27263

AB040961

AC005522

AC007078

AK023924

AY225124

AY225125

BAA96052

BAB14727

BC008856

BC018555

BC026059

BC093079

CCDS43605

CCDS5587

DQ010329

DTX2

DTX2-201

DTX2-202

DTX2-206

DTX2-212

ENSG00000091073

ENSP00000322885

ENSP00000390218

ENSP00000392545

ENSP00000411986

ENST00000324432

ENST00000413936

ENST00000430490

ENST00000446820

EntrezGene:113878

GE85812

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0007219

GO:0008270

GO:0016567

GO:0016740

GO:0031965

GO:0046872

HGNC:15973

HPA042931

Hs.187058

Hs.89135.2.S1_3p_a_at

Hs.89135.2.S1_3p_x_at

ILMN_1659104

ILMN_1744129

ILMN_2275098

IPR001841

IPR004170

IPR013083

IPR018123

IPR018957

MIM:613141

NM_001102594

NM_001102595

NM_001102596

NM_020892

NP_001096064

NP_001096065

NP_001096066

NP_065943

PF00097

PF02825

PH_hs_0027181

Q75MM6

SM00184

SM00678

TC07003309.hg

uc003uff.5

uc003ufg.5

uc003ufh.5

uc003ufj.5

UPI00001413A2

UPI00003674C1

XM_005250131

XM_005250132

XM_011515772

XM_011515773

XM_011515774

XM_011515775

XM_017011723

XM_017011724

XM_017011725

XM_017011726

XM_017011727

XM_017011728

XP_005250188

XP_005250189

XP_011514074

XP_011514075

XP_011514076

XP_011514077

XP_016867212

XP_016867213

XP_016867214

XP_016867215

XP_016867216

XP_016867217

Participant Of

hasCandidate

DTX [cytosol]

Inferred To

Homologues of DTX2 [cytosol] (Danio rerio)

Homologues of DTX2 [cytosol] (Sus scrofa)

Homologues of DTX2 [cytosol] (Xenopus tropicalis)

DTX2 [cytosol] (Bos taurus)

DTX2 [cytosol] (Danio rerio)

DTX2 [cytosol] (Drosophila melanogaster)

DTX2 [cytosol] (Gallus gallus)

DTX2 [cytosol] (Mus musculus)

DTX2 [cytosol] (Rattus norvegicus)

DTX2 [cytosol] (Sus scrofa)

DTX2 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

XP_016867214.1, XP_011514074.1, XP_011514077.1, NP_001096066.1, XP_016867216.1, XP_016867213.1, XP_005250188.1, XP_005250189.1, XP_011514076.1, NP_001096064.1, NP_001096065.1, XP_016867215.1, XP_016867212.1, XP_011514075.1, NP_065943.2

Brenda

2.3.2.27

GeneCards

Q86UW9

PRO

Q86UW9

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8IVS8 GLYCTK	1	GLYCTK [cytosol] (R-HSA-6799244)	0.696	5
UniProt:Q14192 FHL2	1	FHL2 [nucleoplasm] (R-HSA-561161)	0.556	6
UniProt:Q08379 GOLGA2	3	GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.556	3
UniProt:P63165 SUMO1	60	RANGAP1-G97-SUMO1 [nucleoplasm] (R-HSA-3730796) DDX17-G97-SUMO1 [nucleoplasm] (R-HSA-3900210) AURKA-G97-SUMO1 [cytosol] (R-HSA-4655413) TOP2B-G97-SUMO1 [nucleoplasm] (R-HSA-4641311) TOP1-G97-SUMO1 [nucleoplasm] (R-HSA-4641306) TOP2A-G97-SUMO1 [nucleoplasm] (R-HSA-4641341) K254-PCNA-G97-SUMO1 [nucleoplasm] (R-HSA-4615853) K-PCNA-G97-SUMO1 [nucleoplasm] (R-HSA-4615836) K164-PCNA-G97-SUMO1 [nucleoplasm] (R-HSA-4615951) MDC1-G97-SUMO1 [nucleoplasm] (R-HSA-4570527) STAG2-G97-SUMO1 [nucleoplasm] (R-HSA-3826645) RAD21-G97-SUMO1 [nucleoplasm] (R-HSA-3826574) K411-RAD52-G97-SUMO1 [nucleoplasm] (R-HSA-4568857) K412-RAD52-G97-SUMO1 [nucleoplasm] (R-HSA-4568850) K414-RAD52-G97-SUMO1 [nucleoplasm] (R-HSA-4568900) XRCC4-G97-SUMO1 [nucleoplasm] (R-HSA-4568869) K160-PML-G97-SUMO1 [nucleoplasm] (R-HSA-3730884) K490-PML-G97-SUMO1 [nucleoplasm] (R-HSA-3730833) K65-PML-G97-SUMO1 [nucleoplasm] (R-HSA-3730879) K203-PARP1-G97-SUMO1 [nucleoplasm] (R-HSA-4551625) K486-PARP1-G97-SUMO1 [nucleoplasm] (R-HSA-4551748) K496-WRN-G97-SUMO1 [nucleoplasm] (R-HSA-4568906) K898-WRN-G97-SUMO1 [nucleoplasm] (R-HSA-4568893) K356-WRN-G97-SUMO1 [nucleoplasm] (R-HSA-4568845) RNF168-SUMO1 [nucleoplasm] (R-HSA-4551631) XPC-G97-SUMO1 [nucleoplasm] (R-HSA-4570452) TDG-G97-SUMO1 [nucleoplasm] (R-HSA-4551682) SP100-G97-SUMO1 [nucleoplasm] (R-HSA-3730794) BRCA1-G97-SUMO1 [nucleoplasm] (R-HSA-3730735) HIC1-G97-SUMO1 [nucleoplasm] (R-HSA-4570544) TP53BP1-G97-SUMO1 [nucleoplasm] (R-HSA-3730731) SP3-G97-SUMO1 [nucleoplasm] (R-HSA-3730646) K423-MITF-G97-SUMO1 [nucleoplasm] (R-HSA-3730755) K289-MITF-G97-SUMO1 [nucleoplasm] (R-HSA-3730738) K25-FOXL2-G97-SUMO1 [nucleoplasm] (R-HSA-3968400) K150-FOXL2-G97-SUMO1 [nucleoplasm] (R-HSA-3968382) K114-FOXL2-G97-SUMO1 [nucleoplasm] (R-HSA-3968396) HNRNPC-G97-SUMO1 [nucleoplasm] (R-HSA-4570515) K497-NOP58-G97-SUMO1 [nucleoplasm] (R-HSA-4570504) K467-NOP58-G97-SUMO1 [nucleoplasm] (R-HSA-4570462) K84-CBX5-G97-SUMO1 [nucleoplasm] (R-HSA-4615838) K-CBX5-G97-SUMO1 [nucleoplasm] (R-HSA-4615955) K476-HDAC1-G97-SUMO1 [nucleoplasm] (R-HSA-4615867) K444-HDAC1-G97-SUMO1 [nucleoplasm] (R-HSA-4616028) CBX4-G97-SUMO1 [nucleoplasm] (R-HSA-4551756) HDAC2-G97-SUMO1 [nucleoplasm] (R-HSA-4616032) SUZ12-G97-SUMO1 [nucleoplasm] (R-HSA-4615961) SATB1-G97-SUMO1 [nucleoplasm] (R-HSA-4615877) HDAC4-G97-SUMO1 [nucleoplasm] (R-HSA-4615956) K1971-CHD3-G97-SUMO1 [nucleoplasm] (R-HSA-8956370) HIST1H4-G97-SUMO1 [nucleoplasm] (R-HSA-4570549) BMI1-G97-SUMO1 [nucleoplasm] (R-HSA-4551654) TFAP2B-G97-SUMO1 [nucleoplasm] (R-HSA-3730839) TFAP2C-G97-SUMO1 [nucleoplasm] (R-HSA-3730823) TFAP2A-1-G97-SUMO1 [nucleoplasm] (R-HSA-3730825) SUMO1(2-101) [nucleoplasm] (R-HSA-2990831) SUMO1 [nucleoplasm] (R-HSA-877304) UBA2-G97-SUMO1 [nucleoplasm] (R-HSA-3730616) UBE2I-G97-SUMO1 [nucleoplasm] (R-HSA-3730622) HERC2-SUMO1 [nucleoplasm] (R-HSA-4551761)	0.556	3
UniProt:O43521 BCL2L11	7	BCL2L11-BRAF fusion [cytosol] (R-HSA-6802276) BCL2L11 [mitochondrial outer membrane] (R-HSA-2976674) p-BCL2L11-BRAF fusion [cytosol] (R-HSA-6802519) p-S65-BCL2L11 [cytosol] (R-HSA-2976671) p-BCL2L11 [mitochondrial outer membrane] (R-HSA-3145027) p-BCL2L11 [cytosol] (R-HSA-140525) BCL2L11 [cytosol] (R-HSA-2976673)	0.488	2
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.488	4
UniProt:Q15436 SEC23A	4	SEC23A [ER to Golgi transport vesicle membrane] (R-HSA-204024) p-S742,T747 SEC23A [cytosol] (R-HSA-5685740) SEC23A [cytosol] (R-HSA-203972) SEC23A [endoplasmic reticulum membrane] (R-HSA-203976)	0.488	2
UniProt:O14964 HGS	1	HGS [cytosol] (R-HSA-182954)	0.488	2
UniProt:P14652 HOXB2	1	HOXB2 [nucleoplasm] (R-HSA-5617487)	0.488	2
UniProt:Q9BQ95 ECSIT	2	ECSIT [mitochondrial inner membrane] (R-HSA-5689047) ECSIT [cytosol] (R-HSA-168064)	0.488	2
UniProt:Q02548 PAX5	1	PAX5 [nucleoplasm] (R-HSA-158583)	0.488	2