proMMP13 can be activated by plasmin and trypsin initially cleaving at Lys57-Glu58 followed by autoproteolysis at Glu103-Tyr104 (Knauper et al. 1996a).
Atkinson, SJ, Smith, B, López-Otin, C, Hembry, RM, Knäuper, V, Murphy, G, Will, H, Stanton, H
serine-type endopeptidase activity of Trypsin, plasmin [extracellular region]
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