Reactome | MMP1(20-469) [extracellular region]

MMP1(20-469) [extracellular region]

Stable Identifier

R-HSA-1602455

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

proMMP1, Pro Matrix metalloproteinase-1, Interstitial collagenase, Fibroblast collagenase

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P03956 MMP1

Gene Names

MMP1, CLG

Chain

signal peptide:1-19, propeptide:20-99, chain:100-469, chain:100-269, chain:270-469

Reference Genes

BioGPS Gene:4312 MMP1

COSMIC (genes):MMP1 MMP1

CTD Gene:4312 MMP1

dbSNP Gene:4312 MMP1

ENSEMBL:ENSG00000196611.6 MMP1

HGNC:7155 MMP1

KEGG Gene (Homo sapiens):4312 MMP1

Monarch:4312 MMP1

NCBI Gene:4312 MMP1

OMIM:120353 MMP1

UCSC:P03956 MMP1

Reference Transcript

RefSeq:NM_002421.3 MMP1

Other Identifiers

0004010068

11741897_a_at

11755928_s_at

16743721

204475_PM_at

204475_at

3388808

3388809

3388810

3388812

3388813

3388814

3388815

3388817

3388818

3388819

3388820

3388821

3388822

3388825

3388826

3388827

38428_at

4312

7951271

A_23_P1691

GE80495

GO:0003674

GO:0004175

GO:0004222

GO:0004252

GO:0005575

GO:0005576

GO:0006508

GO:0008150

GO:0008233

GO:0008237

GO:0008270

GO:0016787

GO:0022617

GO:0030198

GO:0030312

GO:0030574

GO:0031012

GO:0031334

GO:0043167

GO:0046872

GO:0065003

GO:0071492

HMNXSV003004752

ILMN_1726448

PH_hs_0004751

TC11002234.hg

TC11003311.hg

TC11003312.hg

X54925_at

g13027798_3p_at

Participates

as an input of

Initial activation of proMMP1 (Homo sapiens)

Other forms of this molecule

MMP1(20-53) [extracellular region]

MMP1(54-83) [extracellular region]

MMP1(54-469) [extracellular region]

MMP1(84-469) [extracellular region]

MMP1(100-469) [extracellular region]

Inferred To

MMP1(20-469) [extracellular region] (Caenorhabditis elegans)

MMP1(20-469) [extracellular region] (Canis familiaris)

MMP1(20-469) [extracellular region] (Drosophila melanogaster)

MMP1(20-469) [extracellular region] (Mus musculus)

MMP1(20-469) [extracellular region] (Sus scrofa)

MMP10 [extracellular region] (Gallus gallus)

mmp1 [extracellular region] (Xenopus tropicalis)

Homologues of MMP1(20-469) [extracellular region] (Caenorhabditis elegans)

Homologues of MMP1(20-469) [extracellular region] (Drosophila melanogaster)

Homologues of MMP1(20-469) [extracellular region] (Gallus gallus)

Homologues of MMP1(20-469) [extracellular region] (Xenopus tropicalis)

Mmp1 [extracellular region] (Drosophila melanogaster)

Mmp1 [extracellular region] (Rattus norvegicus)

LOC100489735 [extracellular region] (Xenopus tropicalis)

MMP1 [extracellular region] (Bos taurus)

MMP1 [extracellular region] (Gallus gallus)

mmp8 [extracellular region] (Xenopus tropicalis)

zmp-5 [extracellular region] (Caenorhabditis elegans)

Cross References

RefSeq

NP_002412.1

ZINC - World Drugs

MMP1_HUMAN

Guide to Pharmacology - Targets

1628

OpenTargets

ENSG00000196611

ZINC - FDA approved

MMP1_HUMAN

ZINC - Substances

MMP1_HUMAN

ZINC target

P03956

ZINC - Biogenic

MMP1_HUMAN

PRO

P03956

PDB

4AYK, 1AYK, 1CGF, 1HFC, 2J0T, 966C, 3SHI, 2TCL, 2CLT, 1CGE, 2AYK, 3AYK, 1SU3, 1CGL, 4AUO

ZINC - Investigational

MMP1_HUMAN

ZINC - Metabolites

MMP1_HUMAN

HPA

ENSG00000196611-MMP1

GeneCards

P03956

Ensembl

ENSP00000322788, ENST00000315274, ENSG00000196611

Pharos - Targets

P03956

Orphanet

21204

ZINC - Predictions - Purchasable

MMP1_HUMAN

HMDB Protein

HMDBP02457

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