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PLA2G2A [extracellular region]
Stable Identifier
R-HSA-1602364
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Group IIA phospholipase A2, Non-pancreatic secretory phospholipase A2
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Antimicrobial peptides (Homo sapiens)
PLA2G2A binds bacterial phospholipids (Homo sapiens)
PLA2G2A:Ca2+ [extracellular region] (Homo sapiens)
PLA2G2A [extracellular region] (Homo sapiens)
PLA2G2A:phospholipids [extracellular region] (Homo sapiens)
PLA2G2A:Ca2+ [extracellular region] (Homo sapiens)
PLA2G2A [extracellular region] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
Glycerophospholipid biosynthesis (Homo sapiens)
Acyl chain remodelling of PC (Homo sapiens)
PC is hydrolyzed to 1-acyl LPC by PLA2[16] (Homo sapiens)
PLA2(16) [extracellular region] (Homo sapiens)
PLA2G2A:Ca2+ [extracellular region] (Homo sapiens)
PLA2G2A [extracellular region] (Homo sapiens)
Acyl chain remodelling of PE (Homo sapiens)
PE is hydrolyzed to 1-acyl LPE by PLA2[16] (Homo sapiens)
PLA2(16) [extracellular region] (Homo sapiens)
PLA2G2A:Ca2+ [extracellular region] (Homo sapiens)
PLA2G2A [extracellular region] (Homo sapiens)
Acyl chain remodelling of PG (Homo sapiens)
PG is hydrolyzed to 1-acyl LPG by PLA2[16] (Homo sapiens)
PLA2(16) [extracellular region] (Homo sapiens)
PLA2G2A:Ca2+ [extracellular region] (Homo sapiens)
PLA2G2A [extracellular region] (Homo sapiens)
Acyl chain remodelling of PI (Homo sapiens)
PI is hydrolyzed to 1-acyl LPI by PLA2[15] (Homo sapiens)
PLA2(15) [extracellular region] (Homo sapiens)
PLA2G2A:Ca2+ [extracellular region] (Homo sapiens)
PLA2G2A [extracellular region] (Homo sapiens)
Acyl chain remodelling of PS (Homo sapiens)
PS is hydrolyzed to 1-acyl LPS by PLA2[15] (Homo sapiens)
PLA2(15) [extracellular region] (Homo sapiens)
PLA2G2A:Ca2+ [extracellular region] (Homo sapiens)
PLA2G2A [extracellular region] (Homo sapiens)
Synthesis of PA (Homo sapiens)
PA is hydrolyzed to 1-acyl LPA by PLA2[15] (Homo sapiens)
PLA2(15) [extracellular region] (Homo sapiens)
PLA2G2A:Ca2+ [extracellular region] (Homo sapiens)
PLA2G2A [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P14555 PLA2G2A
Gene Names
PLA2G2A, PLA2B, PLA2L, RASF-A
Chain
signal peptide:1-20, chain:21-144
Reference Genes
BioGPS Gene:5320 PLA2G2A
COSMIC (genes):PLA2G2A PLA2G2A
CTD Gene:5320 PLA2G2A
dbSNP Gene:5320 PLA2G2A
ENSEMBL:ENSG00000188257 PLA2G2A
ENSEMBL_homo_sapiens_GENE:ENSG00000188257.12 PLA2G2A
HGNC:9031 PLA2G2A
KEGG Gene (Homo sapiens):5320 PLA2G2A
Monarch:5320 PLA2G2A
NCBI Gene:5320 PLA2G2A
OMIM:172411 PLA2G2A
UCSC:P14555 PLA2G2A
Reference Transcript
RefSeq:NM_001161727.1 PLA2G2A
RefSeq:NM_001161729.1 PLA2G2A
RefSeq:NM_000300.3 PLA2G2A
RefSeq:NM_001161728.1 PLA2G2A
Other Identifiers
11718416_a_at
11754033_a_at
11757057_x_at
16682771
203649_PM_s_at
203649_s_at
2400028
2400029
2400030
2400033
2400035
2400036
2400038
2400039
2400040
2400042
2400043
2400046
37017_at
5320
614_at
7913216
A_23_P321949
GE57869
GO:0002376
GO:0003824
GO:0004623
GO:0005509
GO:0005543
GO:0005576
GO:0005615
GO:0005739
GO:0005741
GO:0005783
GO:0005789
GO:0005886
GO:0006629
GO:0006644
GO:0006954
GO:0007155
GO:0008152
GO:0008289
GO:0010744
GO:0016020
GO:0016042
GO:0016787
GO:0023052
GO:0030141
GO:0030154
GO:0031410
GO:0031640
GO:0034374
GO:0036335
GO:0042130
GO:0042742
GO:0043226
GO:0046337
GO:0046470
GO:0046473
GO:0046872
GO:0047498
GO:0048471
GO:0050482
GO:0050729
GO:0050830
GO:0070062
GO:0070374
GO:0098542
GO:1902563
HMNXSV003039090
ILMN_1740586
M22430_at
TC01002307.hg
g4505848_3p_s_at
Participates
as a component of
PLA2G2A:Ca2+ [extracellular region] (Homo sapiens)
Other forms of this molecule
PLA2G2A [endoplasmic reticulum membrane]
Inferred To
Homologues of PLA2G2A [extracellular region]
(Caenorhabditis elegans)
Homologues of PLA2G2A [extracellular region]
(Xenopus tropicalis)
PLA2G2A [extracellular region]
(Bos taurus)
PLA2G2A [extracellular region]
(Caenorhabditis elegans)
PLA2G2A [extracellular region]
(Drosophila melanogaster)
PLA2G2A [extracellular region]
(Gallus gallus)
PLA2G2A [extracellular region]
(Mus musculus)
PLA2G2A [extracellular region]
(Rattus norvegicus)
PLA2G2A [extracellular region]
(Sus scrofa)
PLA2G2A [extracellular region]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001155200.1
,
NP_000291.1
,
NP_001155201.1
,
NP_001155199.1
Guide to Pharmacology - Targets
1417
OpenTargets
ENSG00000188257
ZINC - Substances
PA2GA_HUMAN
ZINC - Biogenic
PA2GA_HUMAN
ZINC target
P14555
PRO
P14555
PDB
1DB4
,
3U8D
,
1DB5
,
3U8B
,
1KQU
,
5G3N
,
1N29
,
1KVO
,
1N28
,
1POD
,
3U8H
,
1J1A
,
1AYP
,
1POE
,
3U8I
,
1DCY
,
1BBC
ZINC - Investigational
PA2GA_HUMAN
GeneCards
P14555
HPA
ENSG00000188257-PLA2G2A
Ensembl
ENST00000482011
,
ENST00000400520
,
ENSG00000188257
,
ENSP00000504762
,
ENSP00000364252
,
ENSP00000383364
,
ENST00000375111
Pharos - Targets
P14555
ZINC - Predictions - Purchasable
PA2GA_HUMAN
HMDB Protein
HMDBP00072
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