FBXW7 R505/387C mutant

Stable Identifier
R-HSA-1602342
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
Synonyms
FBXW7 Arg505/387Cys mutant
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
17646409 FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors

O'Neil, J, Grim, J, Strack, P, Rao, S, Tibbitts, D, Winter, C, Hardwick, J, Welcker, M, Meijerink, JP, Pieters, R, Draetta, G, Sears, R, Clurman, BE, Look, AT

J Exp Med 2007
Participants
Participant Of
Disease
Name Identifier Synonyms
T-cell leukemia 715
cancer 162 malignant tumor, malignant neoplasm, primary cancer
Cross References
COSMIC