FBXW7 R479/361Q mutant [nucleoplasm]

Stable Identifier
R-HSA-1602324
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
Synonyms
FBXW7 Arg479/361Gln mutant
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
17646409 FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors

Draetta, G, Rao, S, Sears, R, Strack, P, Tibbitts, D, Hardwick, J, Pieters, R, Look, AT, Welcker, M, Meijerink, JP, Winter, C, Grim, J, O'Neil, J, Clurman, BE

J Exp Med 2007
Participants
Participates
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
T-cell leukemia DOID:715
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