Reactome | GGCX [endoplasmic reticulum membrane]

GGCX [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-159860

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

vitamin K-dependent gamma-carboxylase, gamma-glutamyl carboxylase

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External Reference Information

External Reference

UniProt:P38435 GGCX

Gene Names

GGCX, GC

Chain

initiator methionine:, chain:2-758

Reference Genes

BioGPS Gene:2677 GGCX

COSMIC (genes):GC GGCX

COSMIC (genes):GGCX GGCX

CTD Gene:2677 GGCX

dbSNP Gene:2677 GGCX

ENSEMBL:ENSG00000115486 GGCX

HGNC:4247 GGCX

Monarch:2677 GGCX

NCBI Gene:2677 GGCX

OMIM:137167 GGCX

UCSC:P38435 GGCX

Reference Transcript

Other Identifiers

11729245_a_at

11729246_x_at

11752210_x_at

16899686

205351_PM_at

205351_at

213705_PM_at

213705_at

214005_PM_at

214005_at

214006_PM_s_at

214006_s_at

235413_3p_at

235413_PM_at

235413_at

2562331

2562333

2562334

2562336

2562337

2562338

2562340

2562342

2562344

2562345

2562346

2562347

2562348

2562349

2562350

2562351

2562352

2562353

2562354

2562355

2562356

2562358

2562359

2562360

2562361

2562362

2562363

2562364

2562365

2562366

2562367

2562368

2562370

2562371

2562372

2562374

2562375

2677

37340_at

40394_at

73689_at

8053429

A_32_P113603

A_32_P181103

A_32_P221337

GE57655

GO:0003824

GO:0005783

GO:0005789

GO:0006766

GO:0007596

GO:0008488

GO:0016020

GO:0016829

GO:0017187

GO:0019842

GO:0036211

GO:0042373

GO:0043226

HMNXSV003033103

HMNXSV003050549

Hs.122364.0.A1_3p_at

Hs.122364.0.A1_3p_x_at

Hs.77502.1.A1_3p_at

Hs.77719.1.S1_3p_a_at

Hs.77719.1.S1_3p_at

ILMN_1758232

L17128_at

PH_hs_0031337

TC02002043.hg

TC03002469.hg

g4503984_3p_at

Inferred To

GGCX [endoplasmic reticulum membrane] (Bos taurus)

GGCX [endoplasmic reticulum membrane] (Canis familiaris)

GGCX [endoplasmic reticulum membrane] (Sus scrofa)

ggcx [endoplasmic reticulum membrane] (Xenopus tropicalis)

Ggcx [endoplasmic reticulum membrane] (Mus musculus)

Ggcx [endoplasmic reticulum membrane] (Rattus norvegicus)

Cross References

Guide to Pharmacology - Targets

1268

ENSEMBL

ENST00000233838, ENSP00000408045, ENST00000430215, ENSP00000233838

OpenTargets

ENSG00000115486

HPA

ENSG00000115486-GGCX

ZINC - Substances

VKGC_HUMAN

ZINC target

P38435

PRO

P38435

Pharos - Targets

P38435

GlyGen

P38435

Orphanet

GGCX

HMDB Protein

HMDBP01691

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC5 M	10	M [plasma membrane] (R-COV-9755780) N-glycan M [virion membrane] (R-COV-9694385) M [virion membrane] (R-COV-9694320) M [endocytic vesicle membrane] (R-COV-9694563) N-glycan M [endocytic vesicle membrane] (R-COV-9694738) M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694439) N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694446) M [endoplasmic reticulum membrane] (R-COV-9767620) nascent M [endoplasmic reticulum lumen] (R-COV-9694279) N-glycan M [endoplasmic reticulum membrane] (R-COV-9694684)	0.527	2

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