Expression of PEO1

Stable Identifier
R-HSA-1592239
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, mitochondrial matrix
Synonyms
Expression of Twinkle
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Expression of PEO1
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The PEO1 (TWINKLE) gene is transcribed to yield mRNA and the mRNA is translated in the cytosol to yield precursor protein. PEO1 is imported into the mitochondrial matrix where it may play a role in DNA replication.
Literature References
PubMed ID Title Journal Year
19951946 Nuclear respiratory factor 2 induces the expression of many but not all human proteins acting in mitochondrial DNA transcription and replication

Cantatore, P, Gadaleta, MN, Roberti, M, Polosa, PL, Bruni, F

J Biol Chem 2010
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
NRF2 [nucleoplasm] (Homo sapiens)
Authored
May, B  (2011-08-20)
Reviewed
Lezza, AM  (2013-12-07)
Created
May, B  (2011-09-09)
Cite Us!