As inferred from mouse, NRF2 binds the promoter of the GABPA (NRF2 alpha subunit) gene and enhances transcription.
The GABPA (NRF2 alpha subunit) gene is transcribed to yield mRNA and the mRNA is translated to yield protein. Two subunits of GABPA bind two subunits of GABPB1 to form Nuclear respiratory factor 2 (NRF2).
Virbasius, JV, Gugneja, S, Scarpulla, RC
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