Reactome | SSBP1 [mitochondrial matrix]

SSBP1 [mitochondrial matrix]

Stable Identifier

R-HSA-1592217

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

Single-stranded DNA-binding protein, mitochondrial, SSBP_HUMAN, mtSSB

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q04837 SSBP1

Gene Names

SSBP1, SSBP

Chain

transit peptide:1-16, chain:17-148

Reference Genes

BioGPS Gene:6742 SSBP1

COSMIC (genes):SSBP1 SSBP1

CTD Gene:6742 SSBP1

dbSNP Gene:6742 SSBP1

ENSEMBL:ENSG00000106028 SSBP1

HGNC:11317 SSBP1

KEGG:hsa:6742 SSBP1

Monarch:6742 SSBP1

NCBI Gene:6742 SSBP1

OMIM:600439 SSBP1

UCSC:Q04837 SSBP1

Reference Transcript

Other Identifiers

11728760_a_at

11750014_x_at

1562442_PM_a_at

1562442_a_at

17052394

202591_PM_s_at

202591_s_at

3027916

3027917

3027918

3027919

3027921

3027922

3027923

3027924

3027925

3027926

3027928

3027929

3027930

3027931

3027932

3027934

3027935

3027936

3027937

3027938

3027941

38846_at

39086_g_at

6742

8136631

A_14_P120224

A_14_P200233

A_23_P31536

A_24_P913132

GE58159

GO:0003677

GO:0003682

GO:0003697

GO:0003723

GO:0005515

GO:0005634

GO:0005739

GO:0005759

GO:0006260

GO:0006264

GO:0006268

GO:0007005

GO:0042645

GO:0042802

GO:0042803

GO:0043226

GO:0051096

GO:0051289

GO:0065003

GO:0070062

GO:0090297

HMNXSV003007658

HMNXSV003024799

Hs2.291324.1.S1_3p_s_at

ILMN_1809478

M94556_at

PH_hs_0000115

PH_hs_0038958

TC07000892.hg

g4507230_3p_s_at

Participates

as an output of

Expression of SSBP1 (Homo sapiens)

as a member of

as a component of

SSBP1 tetramer [mitochondrial matrix] (Homo sapiens)

Inferred To

ssbp1 [mitochondrial matrix] (Xenopus tropicalis)

Ssbp1 [mitochondrial matrix] (Mus musculus)

Ssbp1 [mitochondrial matrix] (Rattus norvegicus)

rim1 [mitochondrial matrix] (Schizosaccharomyces pombe)

mtss-1 [mitochondrial matrix] (Caenorhabditis elegans)

SSBP1 [mitochondrial matrix] (Bos taurus)

SSBP1 [mitochondrial matrix] (Canis familiaris)

SSBP1 [mitochondrial matrix] (Gallus gallus)

SSBP1 [mitochondrial matrix] (Sus scrofa)

mtSSB [mitochondrial matrix] (Drosophila melanogaster)

RIM1 [mitochondrial matrix] (Saccharomyces cerevisiae)

Cross References

OpenTargets

ENSG00000106028

ENSEMBL

ENSP00000458815, ENSP00000265304, ENST00000481508, ENST00000484178, ENST00000570667, ENSP00000419541, ENSP00000459208, ENSP00000419665, ENST00000612337, ENST00000575059, ENSP00000419388, ENST00000574199, ENST00000576834, ENSG00000106028, ENST00000465582, ENST00000571430, ENSP00000459367, ENSP00000460028, ENSP00000420485, ENSG00000262771, ENST00000265304, ENSP00000461884, ENST00000498107, ENSP00000480488

HPA

ENSG00000106028-SSBP1

GeneCards

SSBP1

PRO

Q04837

Pharos - Targets

Q04837

GlyGen

Q04837

Orphanet

SSBP1

PDB

3ULL, 2DUD, 1S3O, 8UZT, 6RUP

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q04837 SSBP1	1	SSBP1 [mitochondrial matrix] (R-HSA-1592217)	0.667	3
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.615	11
UniProt:P04618 rev	3	REV (P04618) protein [extracellular region] (R-HIV-174998) REV (P04618) protein [nucleoplasm] (R-HIV-175380) REV (P04618) protein [cytosol] (R-HIV-173267)	0.558	3
UniProt:Q7L8S5 OTU6A			0.556	3
UniProt:O75603 GCM2			0.556	3
UniProt:P47929 LGALS7	1	LGALS7 [cytosol] (R-HSA-9861116)	0.556	6
UniProt:P10636-8 MAPT	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400)	0.527	4
UniProt:Q14197 MRPL58	2	ICT1 [mitochondrial inner membrane] (R-HSA-5624366) ICT1 [mitochondrial matrix] (R-HSA-5368175)	0.527	2
UniProt:Q96PV0 SYNGAP1	1	SYNGAP1 [cytosol] (R-HSA-5658217)	0.527	3
UniProt:Q99IB8-PRO_0000045602			0.462	3