Reactome | Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC

Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC

Stable Identifier

R-HSA-159046

Type

Reaction [transition]

Species

Homo sapiens

Compartment

nuclear envelope, cytosol, nucleoplasm

ReviewStatus

5/5

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Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC

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Once the transport complex is fully assembled the mature mRNA can be translocated from the nucleoplasm to the cytoplasm. The assembled complex starts at the nucleoplasmic basket, travels through the pore, and ends it journey at the cytoplasmic face of the nuclear pore complex.

Literature References

PubMed ID	Title	Journal	Year
2017161	Regulation of histone mRNA in the unperturbed cell cycle: evidence suggesting control at two posttranscriptional steps. Harris, ME, Bohni, R, Schneiderman, MH, Ramamurthy, L, Schumperli, D, Marzluff, WF	Mol Cell Biol	1991
23804756	Structural and biochemical studies of SLIP1-SLBP identify DBP5 and eIF3g as SLIP1-binding proteins von Moeller, H, Lerner, R, Ricciardi, A, Basquin, C, Marzluff, WF, Conti, E	Nucleic Acids Res.	2013