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Plasmin [extracellular region]
Stable Identifier
R-HSA-158770
Type
Complex
Species
Homo sapiens
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
Activation of Matrix Metalloproteinases (Homo sapiens)
Activation of proMMP10 (Homo sapiens)
proMMP10 activators [extracellular region] (Homo sapiens)
Plasmin [extracellular region] (Homo sapiens)
Activation of proMMP8 (Homo sapiens)
proMMP8 initial activators [extracellular region] (Homo sapiens)
Trypsin, plasmin [extracellular region] (Homo sapiens)
Plasmin [extracellular region] (Homo sapiens)
Initial activation of proMMP1 (Homo sapiens)
proMMP1 initial activators [extracellular region] (Homo sapiens)
Plasmin [extracellular region] (Homo sapiens)
Initial activation of proMMP13 by plasmin and trypsin (Homo sapiens)
Trypsin, plasmin [extracellular region] (Homo sapiens)
Plasmin [extracellular region] (Homo sapiens)
Initial activation of proMMP3 (Homo sapiens)
proMMP3 initial activators [extracellular region] (Homo sapiens)
Plasmin [extracellular region] (Homo sapiens)
Initial activation of proMMP7 by trypsin (Homo sapiens)
MMP7 initial activators [extracellular region] (Homo sapiens)
Plasmin [extracellular region] (Homo sapiens)
E-cadherin degradation by MMP3, MMP7 and plasmin. (Homo sapiens)
MMP3, MMP7, Plasmin [extracellular region] (Homo sapiens)
Plasmin [extracellular region] (Homo sapiens)
HSPG2 (perlecan) degradation by MMP3, plasmin, (MMP12) (Homo sapiens)
MMP3, plasmin, (MMP12) [extracellular region] (Homo sapiens)
Plasmin [extracellular region] (Homo sapiens)
Laminin-332 degradation by laminin-322 degrading extracellular proteinases (Homo sapiens)
Laminin-332 degrading extracellular proteinases [extracellular region] (Homo sapiens)
Plasmin, BMP1 [extracellular region] (Homo sapiens)
Plasmin [extracellular region] (Homo sapiens)
Hemostasis (Homo sapiens)
Dissolution of Fibrin Clot (Homo sapiens)
alpha-2-antiplasmin + plasmin -> alpha-2-antiplasmin:plasmin (Homo sapiens)
Plasmin [extracellular region] (Homo sapiens)
alpha-2-antiplasmin:plasmin [extracellular region] (Homo sapiens)
Plasmin [extracellular region] (Homo sapiens)
crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) (Homo sapiens)
Plasmin [extracellular region] (Homo sapiens)
crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin (Homo sapiens)
Plasmin [extracellular region] (Homo sapiens)
crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin (Homo sapiens)
Plasmin [extracellular region] (Homo sapiens)
fibrin multimer, crosslinked -> fibrin digestion products (plasmin) (Homo sapiens)
Plasmin [extracellular region] (Homo sapiens)
plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [one-chain] catalyst) (Homo sapiens)
Plasmin [extracellular region] (Homo sapiens)
plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [two-chain] catalyst) (Homo sapiens)
Plasmin [extracellular region] (Homo sapiens)
urokinase plasminogen activator (one-chain):uPAR -> urokinase plasminogen activator (two-chain):uPAR (Homo sapiens)
Plasmin [extracellular region] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) (Homo sapiens)
Plasmin proteolyzes IGF:IGFBP-3:ALS (Homo sapiens)
Plasmin [extracellular region] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by PDGF (Homo sapiens)
Extracellular processing of novel PDGFs (Homo sapiens)
serine-type endopeptidases involved in novel PDGF processing [extracellular region] (Homo sapiens)
Plasmin [extracellular region] (Homo sapiens)
Participants
components
PLG(20-580) [extracellular region]
(Homo sapiens)
PLG(581-810) [extracellular region]
(Homo sapiens)
Participates
as a component of
alpha-2-antiplasmin:plasmin [extracellular region] (Homo sapiens)
as an input of
alpha-2-antiplasmin + plasmin -> alpha-2-antiplasmin:plasmin (Homo sapiens)
as an output of
plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [two-chain] catalyst) (Homo sapiens)
crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin (Homo sapiens)
crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin (Homo sapiens)
plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [one-chain] catalyst) (Homo sapiens)
as a member of
MMP3, MMP7, Plasmin [extracellular region] (Homo sapiens)
MMP3, plasmin, (MMP12) [extracellular region] (Homo sapiens)
proMMP3 initial activators [extracellular region] (Homo sapiens)
Trypsin, plasmin [extracellular region] (Homo sapiens)
proMMP1 initial activators [extracellular region] (Homo sapiens)
proMMP10 activators [extracellular region] (Homo sapiens)
Plasmin, BMP1 [extracellular region] (Homo sapiens)
serine-type endopeptidases involved in novel PDGF processing [extracellular region] (Homo sapiens)
as a candidate of
MMP7 initial activators [extracellular region] (Homo sapiens)
Inferred To
Plasmin [extracellular region]
(Bos taurus)
Plasmin [extracellular region]
(Danio rerio)
Plasmin [extracellular region]
(Gallus gallus)
Plasmin [extracellular region]
(Mus musculus)
Plasmin [extracellular region]
(Rattus norvegicus)
Plasmin [extracellular region]
(Xenopus tropicalis)
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