Reactome | CCNE2 [cytosol]

CCNE2 [cytosol]

Stable Identifier

R-HSA-157452

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

G1/S-Specific cyclin E2

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O96020 CCNE2

Gene Names

CCNE2

Chain

chain:1-404

Reference Genes

BioGPS Gene:9134 CCNE2

COSMIC (genes):CCNE2 CCNE2

CTD Gene:9134 CCNE2

dbSNP Gene:9134 CCNE2

ENSEMBL:ENSG00000175305 CCNE2

ENSEMBL_homo_sapiens_GENE:ENSG00000175305.18 CCNE2

HGNC:1590 CCNE2

KEGG Gene (Homo sapiens):9134 CCNE2

Monarch:9134 CCNE2

NCBI Gene:9134 CCNE2

OMIM:603775 CCNE2

UCSC:O96020 CCNE2

Reference Transcript

Other Identifiers

11728300_at

11728301_a_at

17079293

205034_PM_at

205034_at

211814_PM_s_at

211814_s_at

3145108

3145109

3145110

3145111

3145112

3145113

3145115

3145116

3145117

3145118

3145119

3145120

3145121

3145123

3145125

3145126

3145127

3145132

35249_at

8151871

82614_g_at

9134

A_23_P215976

A_33_P3217819

A_33_P3247022

GE54769

GO:0000079

GO:0000082

GO:0000278

GO:0000723

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005813

GO:0005815

GO:0005829

GO:0005856

GO:0006260

GO:0006270

GO:0007049

GO:0007059

GO:0007129

GO:0016538

GO:0019901

GO:0022414

GO:0032200

GO:0032880

GO:0036211

GO:0043226

GO:0051301

GO:0051726

GO:0070192

GO:0097134

GO:0097135

GO:0098772

GO:0140013

HMNXSV003006841

ILMN_1651260

ILMN_2412384

PH_hs_0040024

TC08001438.hg

g4092787_3p_a_at

g4757931_3p_at

Participates

as a member of

CCNE [cytosol] (Homo sapiens)

Other forms of this molecule

Unfolded CCNE2 [cytosol]

CCNE2 [nucleoplasm]

Inferred To

cye-1 [cytosol] (Caenorhabditis elegans)

CCNE2 [cytosol] (Bos taurus)

CCNE2 [cytosol] (Canis familiaris)

CCNE2 [cytosol] (Gallus gallus)

CCNE2 [cytosol] (Sus scrofa)

CycE [cytosol] (Drosophila melanogaster)

ccne2 [cytosol] (Danio rerio)

ccne2 [cytosol] (Xenopus tropicalis)

Ccne2 [cytosol] (Mus musculus)

Ccne2 [cytosol] (Rattus norvegicus)

Cross References

RefSeq

XP_016869448.1, XP_016869446.1, XP_016869447.1, NP_477097.1

OpenTargets

ENSG00000175305

HPA

ENSG00000175305-CCNE2

GeneCards

O96020

Ensembl

ENSP00000429089, ENST00000308108, ENSP00000309181, ENST00000520509, ENSG00000175305

PRO

O96020

Pharos - Targets

O96020

PDB

8HN9

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P24941 CDK2	5	p-Y15-CDK2 [nucleoplasm] (R-HSA-187905) p-CDK2 [nucleoplasm] (R-HSA-68370) CDK2 [cytosol] (R-HSA-157440) CDK2 [nucleoplasm] (R-HSA-68365) p-T160-CDK2 [nucleoplasm] (R-HSA-187967)	0.937	15
UniProt:P38936 CDKN1A	5	p-T145-CDKN1A [cytosol] (R-HSA-198614) p-Y77-CDKN1A [cytosol] (R-HSA-8942601) CDKN1A [cytosol] (R-HSA-182512) CDKN1A [nucleoplasm] (R-HSA-182585) p-S130-CDKN1A [nucleoplasm] (R-HSA-187857)	0.888	8
UniProt:P46527 CDKN1B	8	p-S10 CDKN1B [cytosol] (R-HSA-9632829) p-S10 CDKN1B [nucleoplasm] (R-HSA-9632832) p-T157-CDKN1B [cytosol] (R-HSA-198629) CDKN1B [cytosol] (R-HSA-198622) p-Y88-CDKN1B [cytosol] (R-HSA-8848438) p-Y88-CDKN1B [nucleoplasm] (R-HSA-8942808) p-T187-CDKN1B [nucleoplasm] (R-HSA-187525) CDKN1B [nucleoplasm] (R-HSA-182563)	0.788	6
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	6
UniProt:P61024 CKS1B	1	CKS1B [nucleoplasm] (R-HSA-187533)	0.527	2
UniProt:P12004 PCNA	5	monoSUMO1-K164,K254,K-PCNA [nucleoplasm] (R-HSA-4615861) K63polyUb-K164-PCNA [nucleoplasm] (R-HSA-8943000) ISG-K164,ISG-K168-PCNA [nucleoplasm] (R-HSA-5653768) MonoUb-K164-PCNA [nucleoplasm] (R-HSA-5651986) PCNA [nucleoplasm] (R-HSA-68439)	0.527	3
UniProt:Q08999 RBL2	2	RBL2 [nucleoplasm] (R-HSA-389102) p-T401,S672,S1035-RBL2 [nucleoplasm] (R-HSA-1226084)	0.462	3

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