Regulation of KIF23 (MKLP1) by phosphorylation

Stable Identifier
R-HSA-156673
Type
Reaction
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Regulation of KIF23 (MKLP1) by phosphorylation
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The polo-like kinase PLK1 phosphorylates KIF23 (also known as MKLP1 i.e. mitotic kinesin-like protein 1) on serine residues S904 and S905.

Literature References
PubMed ID Title Journal Year
15199097 Molecular interactions of Polo-like-kinase 1 with the mitotic kinesin-like protein CHO1/MKLP-1

Kuriyama, R, Liu, X, Zhou, T, Erikson, RL

J Cell Sci 2004
Participants
Input
Output
Participates
as an event of
Catalyst Activity

protein serine/threonine kinase activity of p-T210-PLK1 [nucleoplasm]

Physical Entity
p-T210-PLK1 [nucleoplasm] (Homo sapiens)
Activity
protein serine/threonine kinase activity (GO:0004674)
Orthologous Events
Regulation of KIF23 (MKLP1) by phosphorylation (Caenorhabditis elegans)
Regulation of KIF23 (MKLP1) by phosphorylation (Canis familiaris)
Regulation of KIF23 (MKLP1) by phosphorylation (Danio rerio)
Regulation of KIF23 (MKLP1) by phosphorylation (Dictyostelium discoideum)
Regulation of KIF23 (MKLP1) by phosphorylation (Drosophila melanogaster)
Regulation of KIF23 (MKLP1) by phosphorylation (Gallus gallus)
Regulation of KIF23 (MKLP1) by phosphorylation (Mus musculus)
Regulation of KIF23 (MKLP1) by phosphorylation (Rattus norvegicus)
Regulation of KIF23 (MKLP1) by phosphorylation (Schizosaccharomyces pombe)
Regulation of KIF23 (MKLP1) by phosphorylation (Sus scrofa)
Regulation of KIF23 (MKLP1) by phosphorylation (Xenopus tropicalis)
Created
Gillespie, ME  (2004-12-09)
Cite Us!